Thermosensitive Molecular Assemblies from Poly(amidoamine) Dendron-Based Lipids

被引:39
作者
Kono, Kenji [1 ]
Murakami, Etsuo [1 ]
Hiranaka, Yuki [1 ]
Yuba, Eiji [1 ]
Kojima, Chie [2 ]
Harada, Atsushi [1 ]
Sakurai, Kazuo [3 ]
机构
[1] Osaka Prefecture Univ, Dept Appl Chem, Naka Ku, Osaka 5998531, Japan
[2] Osaka Prefecture Univ, Nanosci & Nanotechnol Res Ctr, Res Org 21st Century, Osaka 5998531, Japan
[3] Univ Kitakyushu, Dept Chem Proc & Environm, Kitakyushu, Fukuoka, Japan
关键词
dendrimers; lipids; micelles; thermosensitivity; vesicles; PHASE-TRANSITION; TEMPERATURE; DENDRIMERS; LIPOSOMES; POLY(N-ISOPROPYLACRYLAMIDE); COPOLYMERS; MEMBRANE; RELEASE; PH;
D O I
10.1002/anie.201101007
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The heat is on: Vesicles formed from poly(amidoamine) dendron-based lipids with terminal isobutyramide (IBAM) groups undergo a temperature-dependent structural transition through a change in hydration of the vesicle surface. The vesicles are stable at low temperature, but form aggregates above a specific temperature and transform to inverted rodlike micelles or fused vesicles (see picture; G2/G3=second/third generation). Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
引用
收藏
页码:6332 / 6336
页数:5
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