Synthesis of (Z)-1-bromo-1-alkenes and terminal alkynes from anti-2,3-dibromoalkanoic acids by microwave-induced reaction

被引：50

作者：

Kuang, CX ^{[1
]}

Yang, Q

Senboku, H

Tokuda, M

机构：

[1] Osaka Univ, Grad Sch Engn, Dept Chem Mat, Suita, Osaka 6560871, Japan

[2] Univ Tokyo, Grad Sch Pharmaceut Sci, Dept Biopharmaceut, Bunkyo Ku, Tokyo 1130033, Japan

[3] Hokkaido Univ, Grad Sch Engn, Div Mol Chem, Sapporo, Hokkaido 0608628, Japan

来源：

TETRAHEDRON | 2005年 / 61卷 / 16期

基金：

日本学术振兴会;

关键词：

(Z)-1-bromo-1-alkenes; anti-2,3-dibromoalkanoic acids; terminal alkynes; enynes; microwave irradiation;

D O I：

10.1016/j.tet.2005.02.043

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

(Z)-1-Bromo-1-alkenes were stereoselectively prepared in high yields in a short reaction time by microwave irradiation of the corresponding anti-2,3-dibromoalkanoic acids in a Et3N/DMF system. A one-pot synthesis of terminal alkynes and enynes from 2,3-dibromoalkanoic acids were also developed by microwave-induced reaction. (c) 2005 Elsevier Ltd. All rights reserved.

引用

页码：4043 / 4052

页数：10

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