Synthesis of a spirocyclic amine related to the marine natural products halichlorine and pinnaic acid

被引：18

作者：

Clive, DLJ ^{[1
]}

Wang, H ^{[1
]}

Yu, ML ^{[1
]}

机构：

[1] Univ Alberta, Dept Chem, Edmonton, AB T6G 2G2, Canada

来源：

TETRAHEDRON LETTERS | 2005年 / 46卷 / 16期

基金：

加拿大自然科学与工程研究理事会;

关键词：

halichlorine pinnaic acid; ring closing metathesis; spiro compound; Wittig homologation;

D O I：

10.1016/j.tetlet.2005.02.133

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The bis-ester 5 was elaborated into tricyclic lactam 8, which has previously been converted into the spirotricyclic amine 9, a compound that represents a large portion of the marine natural product halichlorine. (c) 2005 Published by Elsevier Ltd.

引用

页码：2853 / 2855

页数：3

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