Flavonoids in the Poisonous Plant Oxytropis falcata

被引：51

作者：

Chen, Wen-Hao ^{[1
,2
,3
]}

Wang, Rui ^{[1
,2
,3
]}

Shi, Yan-Ping ^{[1
,2
,3
]}

机构：

[1] Chinese Acad Sci, Key Lab Chem NW Plant Resources, Lanzhou 730000, Peoples R China

[2] Chinese Acad Sci, Key Lab Nat Med Gansu Prov, Lanzhou Inst Chem Phys, Lanzhou 730000, Peoples R China

[3] Lanzhou Univ, State Key Lab Appl Organ Chem, Coll Chem & Chem Engn, Lanzhou 730000, Peoples R China

来源：

JOURNAL OF NATURAL PRODUCTS | 2010年 / 73卷 / 08期

基金：

中国国家自然科学基金;

关键词：

ASCOCHYTA-RABIEI; PTEROCARPANS; ANALOGS; ROOTS; ISOFLAVONOIDS; ANTIOXIDANT;

D O I：

10.1021/np100339u

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Three new flavonoids, oxytropisoflavans A (1) and B (2) and (6aR,11aR)-3,8-dihydroxy-9,10-dimethoxypterocarpan (3), together with 30 known flavonoids (4-33), were isolated from the aerial parts and roots of Oxytropis falcata. The absolute configurations of 3 and C-3 in 1 and 2 were deduced by circular dichroism. The structure of flavonoid 2 was confirmed by single-crystal X-ray diffraction analysis and that of flavonoid 3 by total synthesis of its racemate. Oxytropisoflavan A (1) is an unprecedented chalcan-isoflavan biflavonoid, whereas oxytropisoflavan B (2) possesses a rare modified A-ring. Pterocarpan 3 has good radical-scavenging activity in the 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay.

引用

页码：1398 / 1403

页数：6

共 39 条

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