Fluorescein derivative-based, selective and sensitive chemosensor for NADH

被引：16

作者：

Jung, Sang Oh ^{[2
]}

Ahn, Ji Yeon ^{[1
]}

Kim, Sudeok ^{[1
]}

Yi, Sujung ^{[1
]}

Kim, Mi Hee ^{[1
]}

Jang, Hyun Hye ^{[1
]}

Seo, Seong Hyeok ^{[1
]}

Eom, Min Sik ^{[1
]}

Kim, Seung Kyung ^{[1
]}

Ryu, De Hun ^{[1
]}

Chang, Suk-Kyu ^{[1
]}

Han, Min Su ^{[1
]}

机构：

[1] Chung Ang Univ, Dept Chem, Seoul 156756, South Korea

[2] POSTECH, Dept Chem, Pohang 790784, Kyungbuk, South Korea

来源：

TETRAHEDRON LETTERS | 2010年 / 51卷 / 29期

关键词：

LOW-POTENTIAL DETECTION; NICOTINAMIDE ADENINE-DINUCLEOTIDE; GLASSY-CARBON ELECTRODE; ARTIFICIAL RECEPTORS; NANOTUBE COMPOSITE; PHYSIOLOGICAL PH; QUANTUM DOTS; PYROPHOSPHATE; BIOSENSOR; ENZYMES;

D O I：

10.1016/j.tetlet.2010.05.044

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Fluorescein mercury acetate (FMA) derivative can be used as a chemosensor for NADH that plays key roles in cellular energy metabolism and dehydrogenase enzymatic reactions. The sensor recognizes NADH by two mercury metal ions in the compound using the metal-anion interaction and its subsequent binding-induced fluorescence changes of FMA. The FMA can detect an aqueous NADH concentration of approximately 1.0 uM and has a high selectivity over various anions including NAD(+), the oxidized form of NADH. Crown Copyright (C) 2010 Published by Elsevier Ltd. All rights reserved.

引用

页码：3775 / 3778

页数：4

共 56 条

[1] Anion recognition by dimetallic cryptates [J].

Amendola, V ;

Fabbrizzi, L ;

Mangano, C ;

Pallavicini, P ;

Poggi, A ;

Taglietti, A .

COORDINATION CHEMISTRY REVIEWS, 2001, 219 :821-837

[2]

[Anonymous], 1987, BINDING CONSTANTS ME

[3]

[Anonymous], 2002, BIOENERGETICS

[4] An "Off-On" Type UTP/UDP Selective Fluorescent Probe and Its Application to Monitor Glycosylation Process [J].

Chen, Xiaoqiang ;

Jou, Min Jung ;

Yoon, Juyoung .

ORGANIC LETTERS, 2009, 11 (10) :2181-2184

[5] Development of an optical hydrogen sulphide sensor [J].

Choi, MMF ;

Hawkins, P .

SENSORS AND ACTUATORS B-CHEMICAL, 2003, 90 (1-3) :211-215

[6] Chemodosimetric Hg2+-selective signaling by mercuration of dichlorofluorescein derivatives [J].

Choi, Myung Gil ;

Ryu, De Hun ;

Jeon, Hye Lim ;

Cha, Sunyoung ;

Cho, Janggeun ;

Joo, Hyun Hye ;

Hong, Kwan Soo ;

Lee, Chulhyun ;

Ahn, Sangdoo ;

Chang, Suk-Kyu .

ORGANIC LETTERS, 2008, 10 (17) :3717-3720

[7] Low potential detection of NADH at titanium-containing MCM-41 modified glassy carbon electrode [J].

Dai, Zhihui ;

Lu, Guofei ;

Bao, Jianchun ;

Huang, Xiaohua ;

Ju, Huangxian .

ELECTROANALYSIS, 2007, 19 (05) :604-607

[8] A METHOD FOR THE DETERMINATION OF CHANGES OF GLYCOLYTIC METABOLITES IN YEAST ON A SUBSECOND TIME SCALE USING EXTRACTION AT NEUTRAL PH [J].

DEKONING, W ;

VANDAM, K .

ANALYTICAL BIOCHEMISTRY, 1992, 204 (01) :118-123

[9] AMPEROMETRIC HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHIC DETECTION OF NADH AT A BASE-ACTIVATED GLASSY-CARBON ELECTRODE [J].

EISENBERG, EJ ;

CUNDY, KC .

ANALYTICAL CHEMISTRY, 1991, 63 (08) :845-847

[10] The design of luminescent sensors for anions and ionisable analytes [J].

Fabbrizzi, L ;

Licchelli, M ;

Rabaioli, G ;

Taglietti, A .

COORDINATION CHEMISTRY REVIEWS, 2000, 205 :85-108

← 1 2 3 4 5 6 →