Bacteremia: Prevalence and antimicrobial resistance profiling in chronic kidney diseases and renal transplant patients

被引：0

作者：

Jamil, Bushra ^{[1
]}

Bokhari, Mohammad Tauseef Mukhtar ^{[2
]}

Saeed, Azhar ^{[2
]}

Bokhari, Mohammad Zahid Mukhtar ^{[2
]}

Hussain, Zakir ^{[2
]}

Khalid, Tayabba ^{[2
]}

Bukhari, Habib ^{[1
]}

Imran, Muhammad ^{[1
]}

Abbasi, Shahid Ahmad ^{[2
]}

机构：

[1] Comsats Inst Informat Technol, Dept Biosci, Islamabad, Pakistan

[2] Al Sayed Hosp Pvt Ltd Rawalpindi, Rawalpindi, Pakistan

来源：

JOURNAL OF THE PAKISTAN MEDICAL ASSOCIATION | 2016年 / 66卷 / 06期

关键词：

Bacteraemia; Chronic kidney diseases; ESBL; MBL;

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Objective: To determine the prevalence of bacteraemia in patients with chronic kidney disease, particularly those on dialysis and those who had had renal transplant, and to evaluate resistance among the isolated strains. Method: The cross-sectional study was conducted at Kidney Centre, Al-Sayyed Hospital, Rawalpindi, Pakistan, from June to December 2014. Samples that displayed positive growth were separated from the rest. The isolates were then identified and screened for extended spectrum beta lactamases and metallo beta lactamases production and other resistance mechanisms by phenotypic method. Results: Of the 1400 samples, only 46 samples (3.3%) displayed signal for positive growth. The prevalence of extended spectrum beta lactamase (ESBL) producing strains was recorded to be 37%. Carbapenem resistance was witnessed in 15% samples. Whereas, Methicillin-resistant staphylococcus aureus prevalence was detected to be 2%. Conclusion: Resistance in gram-negative microbes was rising, while it was declining in gram-positive microbes.

引用

页码：705 / 709

页数：5

共 18 条

[1]

Abbott KC, 2002, J NEPHROL, V15, P248

[2]

Aggarwal Ritu, 2009, J Lab Physicians, V1, P7, DOI 10.4103/0974-2727.44423

[3]

Allon M, 2004, AM J KIDNEY DIS, V44, P779, DOI 10.1016/S0272-6386(04)01078-9

[4]

[Anonymous], 2014, NAT DIAB STAT REP ES

[5] Epidemiology of methicillin-resistant Staphylococcus aureus [J].

Boucher, Helen W. ;

Corey, G. Ralph .

CLINICAL INFECTIOUS DISEASES, 2008, 46 :S344-S349

[6] Bad Bugs, No Drugs: No ESKAPE! An Update from the Infectious Diseases Society of America [J].

Boucher, Helen W. ;

Talbot, George H. ;

Bradley, John S. ;

Edwards, John E., Jr. ;

Gilbert, David ;

Rice, Louis B. ;

Scheld, Michael ;

Spellberg, Brad ;

Bartlett, John .

CLINICAL INFECTIOUS DISEASES, 2009, 48 (01) :1-12

[7]

Cockerill F.R., 2012, Performance Standards for Antimicrobial Susceptibility Testing: Twenty-Second Informational Supplement

[8] High prevalence of ESBL-producing Escherichia coli isolates among hemodialysis patients in Portugal: appearance of ST410 with the blaCTX-M-14 gene [J].

Correia, Susana ;

Pacheco, Rui ;

Radhouani, Hajer ;

Diniz, Joao Carlos ;

Ponce, Pedro ;

Jones-Dias, Daniela ;

Canica, Manuela ;

Igrejas, Gilberto ;

Poeta, Patricia .

DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE, 2012, 74 (04) :423-425

[9] Comparison of the VersaTREK blood culture system against the Bactec9240 system in patients with suspected bloodstream infections [J].

Dreyer, Andries W. ;

Ismail, Nazir A. ;

Nkosi, Deliwe ;

Lindeque, Kathy ;

Matthews, Marliza ;

van Zyl, Danie G. ;

Hoosen, Anwar A. .

ANNALS OF CLINICAL MICROBIOLOGY AND ANTIMICROBIALS, 2011, 10

[10]

Evans Richard P, 2014, J Bone Joint Surg Am, V96, pe95

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