A Review of Behavioral Tests to Evaluate Different Types of Anxiety and Anti-anxiety Effects

被引：88
作者：
Himanshu [1 ]
Dharmila [2 ]
Sarkar, Deepa [1 ]
Nutan [1 ]
机构：
[1] HIMT Coll Pharm, Greater Noida 201301, Uttar Pradesh, India
[2] Jamia Hamdard, Sch Pharmaceut Educ & Res, New Delhi, India
来源：
CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE | 2020年 / 18卷 / 03期
关键词：
Anxiety; Elevated plus maze; The light and dark box; Marble-burying behavior; The hole-board test; The open-field test; ELEVATED PLUS-MAZE; OBSESSIVE-COMPULSIVE DISORDER; MARBLE-BURYING BEHAVIOR; MODIFIED HOLE BOARD; ANIMAL-MODELS; OPEN-FIELD; PARADIGM; MICE; RATS; DRUGS;
D O I：
10.9758/cpn.2020.18.3.341
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
Behavioral tests are very useful to understand the Neuro-psychotic disease and also helpful in finding the treatment of the particular disease. Nowadays various tests are available to evaluate the anxiolytics effect of a new entity or even for comparative studies with the standard drug. As per the ethics, a new compound or drug believes to have possible pharmacological effects should be tested on animals before tested on humans which have similar physiology than humans. First, rats were used for behavioral test for evaluation of anti-anxiety drug but later on the various strain of mice were added for evaluation of anxiolytics because of better genetic possibilities than rats. In this review article, we have discussed the most commonly used behavioral tests used to evaluate the anti-anxiety effect. Anxiolytics are the agent which are used to elevate anxiety effect produced due to any cause. The various parameter will be undertaken for the better and precise evaluation of anxiolytics.
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收藏
页码：341 / 351
页数：11
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