Diagnostic Testing for Crimean-Congo Hemorrhagic Fever

被引:29
作者
Raabe, Vanessa N. [1 ,2 ]
机构
[1] NYU, Grossman Sch Med, Dept Med, Div Infect Dis & Immunol, New York, NY 10012 USA
[2] NYU, Dept Pediat, Div Pediat Infect Dis, Grossman Sch Med, New York, NY 10012 USA
关键词
Crimean-Congo hemorrhagic fever virus; LINKED-IMMUNOSORBENT-ASSAY; POLYMERASE-CHAIN-REACTION; RIFT-VALLEY FEVER; TIME RT-PCR; REVERSED PASSIVE HEMAGGLUTINATION; IMMUNOGLOBULIN-G ANTIBODIES; VIRAL LOAD; RECOMBINANT NUCLEOPROTEIN; RAPID DETECTION; IGG ANTIBODY;
D O I
10.1128/JCM.01580-19
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Crimean-Congo hemorrhagic fever is the most geographically widespread tick-borne virus, with infection resulting in mortality in up to 30% of cases. Clinical diagnosis alone is difficult due to the nonspecific nature of symptoms; therefore, laboratory diagnostics should be utilized for patients with residence in or travel to regions of endemicity in whom the disease is suspected. This minireview provides an overview of laboratory tests available for Crimean-Congo hemorrhagic fever (CCHF) and their utility in diagnosis with a focus on diagnosing CCHF in humans.
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页数:10
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