Preserving Well-being in Patients With Advanced and Late Prostate Cancer

被引:0
作者
Handley, Nathan R.
Feng, Felix Y.
Guise, Theresa A.
D'Andrea, Denise
Kelly, William Kevin
Gomella, Leonard G.
机构
[1] Thomas Jefferson Univ, Sidney Kimmel Canc Ctr, Dept Med Oncol, Philadelphia, PA 19107 USA
[2] Univ Calif San Francisco, Helen Diller Family Comprehens Canc Ctr, Dept Radiat Oncol, San Francisco, CA 94143 USA
[3] Univ Calif San Francisco, Helen Diller Family Comprehens Canc Ctr, Dept Urol, San Francisco, CA 94143 USA
[4] Univ Calif San Francisco, Helen Diller Family Comprehens Canc Ctr, Dept Med, San Francisco, CA 94143 USA
[5] Indiana Univ Sch Med, Dept Med, Indianapolis, IN 46202 USA
[6] Janssen Sci Affairs LLC, Horsham, PA USA
[7] Thomas Jefferson Univ, Sidney Kimmel Canc Ctr, Dept Urol, Philadelphia, PA 19107 USA
关键词
ANDROGEN-DEPRIVATION THERAPY; ACETATE PLUS PREDNISONE; ABIRATERONE ACETATE; CARDIOVASCULAR-DISEASE; PHYSICAL-ACTIVITY; AMERICAN-SOCIETY; DOUBLE-BLIND; BONE-HEALTH; OLDER MEN; RISK;
D O I
10.1016/j.urology.2020.12.018
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Androgen deprivation therapy, alone or in combination with androgen signaling inhibitors, is a treatment option for patients with advanced prostate cancer (PC). When making treatment decisions, health care providers must consider the long-term effects of treatment on the patient's overall health and well-being. Herein, we review the effects of these treatments on the musculoskeletal and cardiovascular systems, cognition, and fall risk, and provide management approaches for each. We also include an algorithm to help health care providers implement best clinical practices and interdisciplinary care for preserving the overall well-being of PC patients. (C) 2020 Elsevier Inc.
引用
收藏
页码:199 / 209
页数:11
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