Fluorescence of an eosine probe in solutions of human serum albumin with organic and inorganic ligands

被引：7

作者：

Vlasova, I. M. ^{[1
]}

Saletskii, A. M. ^{[1
]}

机构：

[1] Moscow MV Lomonosov State Univ, Fac Phys, Moscow 111992, Russia

来源：

RUSSIAN JOURNAL OF PHYSICAL CHEMISTRY B | 2008年 / 2卷 / 02期

关键词：

Sodium Dodecyl Sulfate; Quantum Yield; Human Serum Albumin; CsCl; Sodium Dodecyl Sulfate Concentration;

D O I：

10.1134/S1990793108020218

中图分类号：

O64 [物理化学（理论化学）、化学物理学]; O56 [分子物理学、原子物理学];

学科分类号：

070203 ; 070304 ; 081704 ; 1406 ;

摘要：

The fluorescence of an eosine molecular probe in solutions of human serum albumin (HSA) in the presence of an inorganic (CsCl) and organic (sodium dodecyl sulfate, SDS) ligand was studied. The interaction of HSA molecules with these ligands was analyzed. It was demonstrated that the presence of CsCl, a low-molecular-weight salt, in the solutions influences the efficiency of the complexation of eosine with HSA. Data on the dynamics of the conformation rearrangement of HSA during denaturation under the action of SDS were obtained.

引用

页码：298 / 301

页数：4

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Vlasova, IM ;

Mikrin, VE ;

Saletsky, AM .

LASER PHYSICS LETTERS, 2005, 2 (04) :204-207

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