Synthesis and molecular recognition of the uridine-containing derivative of p-tert-butylcalix[4]arene

被引：4

作者：

Liang, J

Fu, HY

Liu, Y

Wang, L

Ye, ZF

Shi, XF ^{[1
]}

机构：

[1] Nanjing Univ, State Key Lab Coordinat Chem, Nanjing 210093, Jiangsu, Peoples R China

[2] Tongji Univ, Dept Chem, Shanghai 200092, Peoples R China

来源：

CANADIAN JOURNAL OF CHEMISTRY | 2003年 / 81卷 / 09期

关键词：

calixarene; uridine; molecular recognition; UV-vis spectra;

D O I：

10.1139/V03-125

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The new uridine-containing derivative of p-tert-butylcalix[4]arene-5,11,17,23-tetra-tert-butyl-25,26,27-trihydroxyl-28-oxyuridinecalix[4]arene (CU)-was synthesized and characterized by H-1 NMR, C-13 NMR, IR, EI-MS, and ESI-MS spectra. By the aid of UV-vis spectra, the molecular recognition of CU was studied. The hypochromic effect in UV-vis spectra showed the obvious molecular recognition of CU to ATP. This recognition is actually the hydrogen bond interaction between the uracil group of CU and the base radical of ATP. The association constant between CU and adenine was determined by UV titration at low concentrations.

引用

页码：1019 / 1024

页数：6

共 11 条

[1]

Gutsche C. D., 1989, CALIXARENES MONOGRAP, V1

[2] CALIXARENES .18. SYNTHESIS PROCEDURES FOR PARA-TERT-BUTYLCALIX[4]ARENE [J].