Should high mobility group box-1 protein (HMGBI) be measured in patients with severe sepsis and septic shock? If so, when, where, and how?

被引:5
作者
Eriksson, M [1 ]
机构
[1] Univ Uppsala Hosp, Inst Anesthesia & Crit Care, Uppsala, Sweden
关键词
editorial; endotoxin; high mobility group box-1 protein; immunomodulation; sepsis; septic shock;
D O I
10.1097/01.CCM.0000155995.62327.93
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
引用
收藏
页码:682 / 683
页数:2
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共 13 条
[1]  
Abraham E, 1998, LANCET, V351, P929
[2]   Why immunomodulatory therapies have not worked in sepsis [J].
Abraham, E .
INTENSIVE CARE MEDICINE, 1999, 25 (06) :556-566
[3]   PASSIVE-IMMUNIZATION AGAINST CACHECTIN TUMOR NECROSIS FACTOR PROTECTS MICE FROM LETHAL EFFECT OF ENDOTOXIN [J].
BEUTLER, B ;
MILSARK, IW ;
CERAMI, AC .
SCIENCE, 1985, 229 (4716) :869-871
[4]   Advances in sepsis therapy [J].
Glück T. ;
Opal S.M. .
Drugs, 2004, 64 (8) :837-859
[5]   Experimental human endotoxemia is associated with depression of load-independent contractility indices [J].
Kumar, A ;
Bunnell, E ;
Lynn, M ;
Anel, R ;
Habet, K ;
Neumann, A ;
Parrillo, JE .
CHEST, 2004, 126 (03) :860-867
[6]   Novel therapies for sepsis: antiendotoxin therapies [J].
Manocha, S ;
Feinstein, D ;
Kumar, A ;
Kumar, A .
EXPERT OPINION ON INVESTIGATIONAL DRUGS, 2002, 11 (12) :1795-1812
[7]  
PARKKINEN J, 1993, J BIOL CHEM, V268, P19726
[8]   Persistent elevation of high mobility group box-1 protein (HMGB1) in patients with severe sepsis and septic shock [J].
Sundén-Cullberg, J ;
Norrby-Teglund, A ;
Rouhiainen, A ;
Rauvala, H ;
Herman, G ;
Tracey, KJ ;
Lee, ML ;
Andersson, J ;
Tokics, L ;
Treutiger, CJ .
CRITICAL CARE MEDICINE, 2005, 33 (03) :564-573
[9]   Importance of hemostatic gene polymorphisms for susceptibility to and outcome of severe sepsis [J].
Texereau, J ;
Pene, F ;
Chiche, JD ;
Rousseau, C ;
Mira, JP .
CRITICAL CARE MEDICINE, 2004, 32 (05) :S313-S319
[10]   ANTI-CACHECTIN TNF MONOCLONAL-ANTIBODIES PREVENT SEPTIC SHOCK DURING LETHAL BACTEREMIA [J].
TRACEY, KJ ;
FONG, Y ;
HESSE, DG ;
MANOGUE, KR ;
LEE, AT ;
KUO, GC ;
LOWRY, SF ;
CERAMI, A .
NATURE, 1987, 330 (6149) :662-664