Immunosensing by a synthetic ligand-gated ion channel

被引：0
|
作者：
Terrettaz, S
Ulrich, WP
Guerrini, R
Verdini, A
Vogel, H [1 ]
机构：
[1] Ecole Polytech Fed Lausanne, Lab Chim Phys Polymeres & Membranes, Dept Chim, CH-1015 Lausanne, Switzerland
[2] Univ Ferrara, Dipartimento Sci Farmaceut, I-44100 Ferrara, Italy
[3] Univ Lausanne, Inst Biochim, CH-1066 Epalinges, Switzerland
来源：
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2001年 / 40卷 / 09期
关键词：
D O I：
10.1002/1521-3773(20010504)40:9<1740::AID-ANIE17400>3.0.CO;2-5
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Specific binding of an antibody to its antigen at subnanomolar concentrations has been detected electrically by impedance spectroscopy through changes in the ion-conductance of a synthetic ligand-gated ion channel (SLIC) in a supported lipid bilayer on a gold electrode (see picture).
引用
收藏
页码：1740 / 1743
页数：4
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