PANTON-VALENTINE LEUKOCIDIN PRODUCING STAPHYLOCOCCUS AUREUS FACIAL PYOMYOSITIS CAUSING PARTIAL CAVERNOUS SINUS THROMBOSIS

被引：3

作者：

Green, Katherine ^{[1
]}

Chranioti, Ioanna ^{[2
]}

Singh, Saurabh ^{[3
]}

Jager, Hans Rolf ^{[3
,4
]}

Drebes, Anje ^{[5
]}

Gabbie, Susie ^{[1
]}

Cohen, Jonathan ^{[2
]}

机构：

[1] Royal Free London NHS Fdn Trust, Dept Paediat, London, England

[2] Univ Coll London Hosp NHS Fdn Trust, Paediat & Adolescent Div, 6th Floor Cent,250 Euston Rd, London NW1 2PG, England

[3] UCL, Ctr Med Imaging, London, England

[4] UCL, UCL Inst Neurol, Acad Neuroradiol Unit, London, England

[5] Royal Free London NHS Fdn Trust, KD Haemophilia & Thrombosis Ctr, London, England

来源：

PEDIATRIC INFECTIOUS DISEASE JOURNAL | 2017年 / 36卷 / 11期

关键词：

Panton-Valentine leukocidin; Staphylococcus aureus; pyomyositis; cavernous sinus thrombosis; VENOUS THROMBOSIS; CHILDREN; MANAGEMENT; GUIDELINE;

D O I：

10.1097/INF.0000000000001667

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We present a case of subtotal cavernous sinus thrombosis secondary to Panton-Valentine leukocidin-associated Staphylococcus aureus pyomyositis of the muscles of mastication in a previously healthy child, who was successfully managed with no residual disease. He was found to have a factor V Leiden heterozygous mutation. We highlight the propensity of Panton-Valentine leukocidin Staphylococcus aureus to induce venous thrombosis at any site but with potential for more severe consequences in the head. We highlight pyomyositis as a differential for periorbital cellulitis and discuss the significance of the factor V Leiden mutation.

引用

页码：1102 / 1104

页数：4

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