Mouse Models of Psoriasis: A Comprehensive Review

被引：99

作者：

Gangwar, Roopesh Singh ^{[1
,2
]}

Gudjonsson, Johann E. ^{[3
]}

Ward, Nicole L. ^{[1
,2
]}

机构：

[1] Case Western Reserve Univ, Dept Nutr, Cleveland, OH 44106 USA

[2] Case Western Reserve Univ, Dept Dermatol, Cleveland, OH 44106 USA

[3] Univ Michigan, Dept Dermatol, Ann Arbor, MI 48109 USA

来源：

JOURNAL OF INVESTIGATIVE DERMATOLOGY | 2022年 / 142卷 / 3 PT B期

关键词：

INDUCED SKIN INFLAMMATION; DELTA T-CELLS; NF-KAPPA-B; VASCULAR INFLAMMATION; GENE-EXPRESSION; TRANSGENIC MICE; UNINVOLVED SKIN; ANIMAL-MODEL; IMIQUIMOD; KERATINOCYTE;

D O I：

10.1016/j.jid.2021.06.019

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

The use of preclinical animal models of psoriasis has significantly increased over the last three decades, with each model having unique strengths and limitations. Some models translate better to human disease, and many have provided unique insight into psoriasis disease pathogenesis. In this comprehensive review, we present a comparative description and discussion of genetic mouse models, xenograft approaches, and elicited methods using cytokine injections into and topical imiquimod onto mice. We provide an inclusive list of genetically modified animals that have had imiquimod applied to or cytokines injected into their skin and describe the outcomes of these manipulations. This review will provide a valuable resource for those interested in working with psoriasis animal models.

引用

页码：884 / 897

页数：14

共 107 条

[1] Stimulation of TLR2 and TLR4 differentially skews the balance of T cells in a mouse model of arthritis [J].

Abdollahi-Roodsaz, Shahla ;

Joosten, Leo A. B. ;

Koenders, Marije I. ;

Devesa, Isabel ;

Roelofs, Mieke F. ;

Radstake, Timothy R. D. J. ;

Heuvelmans-Jacobs, Marleen ;

Akira, Shizuo ;

Nicklin, Martin J. H. ;

Ribeiro-Dias, Fatima ;

Van den Berg, Wim B. .

JOURNAL OF CLINICAL INVESTIGATION, 2008, 118 (01) :205-216

[2] IL-23 Is Critical for Induction of Arthritis, Osteoclast Formation, and Maintenance of Bone Mass [J].

Adamopoulos, Iannis E. ;

Tessmer, Marlowe ;

Chao, Cheng-Chi ;

Adda, Sarvesh ;

Gorman, Dan ;

Petro, Mary ;

Chou, Chuan-Chu ;

Pierce, Robert H. ;

Yao, Wei ;

Lane, Nancy E. ;

Laface, Drake ;

Bowman, Edward P. .

JOURNAL OF IMMUNOLOGY, 2011, 187 (02) :951-959

[3] Tristetraprolin expression by keratinocytes controls local and systemic inflammation [J].

Andrianne, Mathieu ;

Assabban, Assiya ;

La, Caroline ;

Mogilenko, Denis ;

Salle, Delphine Staumont ;

Fleury, Sebastien ;

Doumont, Gilles ;

Van Simaeys, Gaetan ;

Nedospasov, Sergei A. ;

Blackshear, Perry J. ;

Dombrowicz, David ;

Goriely, Stanislas ;

Van Maele, Laurye .

JCI INSIGHT, 2017, 2 (11)

[4]

Badanthadka M, 2021, J BASIC CLIN PHYSIOL, DOI [10.1515/jbcpp-2020-011, DOI 10.1515/JBCPP-2020-011]

[5] The genetic difference between C57Bl/6J and C57Bl/6N mice significantly impacts Aldara-induced psoriasiform dermatitis [J].

Bezdek, Siegfried ;

Hdnah, Ashref ;

Sezin, Tanya ;

Mousavi, Sadegh ;

Zillikens, Detlef ;

Ibrahim, Saleh ;

Ludwig, Ralf J. ;

Sadik, Christian D. .

EXPERIMENTAL DERMATOLOGY, 2017, 26 (04) :349-351

[6] KLK6 expression in skin induces PAR1-mediated psoriasiform dermatitis and inflammatory joint disease [J].

Billi, Allison C. ;

Ludwig, Jessica E. ;

Fritz, Yi ;

Rozic, Richard ;

Swindell, William R. ;

Tsoi, Lam C. ;

Gruzska, Dennis ;

Abdollahi-Roodsaz, Shahla ;

Xing, Xianying ;

Diaconu, Doina ;

Uppala, Ranjitha ;

Camhi, Maya, I ;

Klenotic, Philip A. ;

Sarkar, Mrinal K. ;

Husni, M. Elaine ;

Scher, Jose U. ;

McDonald, Christine ;

Kahlenberg, J. Michelle ;

Midura, Ronald J. ;

Gudjonsson, Johann E. ;

Ward, Nicole L. .

JOURNAL OF CLINICAL INVESTIGATION, 2020, 130 (06) :3151-3157

[7] Opposing activities of two novel members of the IL-1 ligand family regulate skin inflammation [J].

Blumberg, Hal ;

Dinh, Huyen ;

Trueblood, Esther S. ;

Pretorius, James ;

Kugler, David ;

Weng, Ning ;

Kanaly, Suzanne T. ;

Towne, Jennifer E. ;

Willis, Cynthia R. ;

Kuechle, Melanie K. ;

Sims, John E. ;

Peschon, Jacques J. .

JOURNAL OF EXPERIMENTAL MEDICINE, 2007, 204 (11) :2603-2614

[8] Spontaneous development of psoriasis in a new animal model shows an essential role for resident T cells and tumor necrosis factor-α [J].

Boyman, O ;

Hefti, HP ;

Conrad, C ;

Nickoloff, BJ ;

Suter, M ;

Nestle, FO .

JOURNAL OF EXPERIMENTAL MEDICINE, 2004, 199 (05) :731-736

[9] SOMATIC EXPRESSION OF HERPES THYMIDINE KINASE IN MICE FOLLOWING INJECTION OF A FUSION GENE INTO EGGS [J].

BRINSTER, RL ;

CHEN, HY ;

TRUMBAUER, M ;

SENEAR, AW ;

WARREN, R ;

PALMITER, RD .

CELL, 1981, 27 (01) :223-231

[10] A HYPOTHESIS ON THE CAUSE OF CHRONIC EPIDERMAL HYPERPROLIFERATION IN ASEBIA MICE [J].

BROWN, WR ;

HARDY, MH .

CLINICAL AND EXPERIMENTAL DERMATOLOGY, 1988, 13 (02) :74-77

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