A Phenylacetylated Peptide, JBIR-96, Isolated from Streptomyces sp RI051-SDHV6

被引：8

作者：

Ueda, Jun-ya ^{[1
]}

Izumikawa, Miho ^{[1
]}

Kozone, Ikuko ^{[1
]}

Yamamura, Hideki ^{[2
]}

Hayakawa, Masayuki ^{[2
]}

Takagi, Motoki ^{[1
]}

Shin-ya, Kazuo ^{[3
]}

机构：

[1] Japan Biol Informat Consortium JBIC, Biomed Informat Res Ctr BIRC, Koto Ku, Tokyo 1350064, Japan

[2] Univ Yamanashi, Interdisciplinary Grad Sch Med & Engn, Kofu, Yamanashi 4008511, Japan

[3] Natl Inst Adv Ind Sci & Technol, Biomed Informat Res Ctr BIRC, Koto Ku, Tokyo 1350064, Japan

来源：

JOURNAL OF NATURAL PRODUCTS | 2011年 / 74卷 / 05期

基金：

日本学术振兴会;

关键词：

METABOLIC PRODUCTS; MICROORGANISMS; INHIBITOR;

D O I：

10.1021/np200054s

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Searching for metabolites from Streptomyces sp. RI051-SDHV6 resulted in the discovery of a novel peptide, JBIR-96 (1). The structure of 1 was established as an N-phenylacetylated pentapeptide involving a cysteic acid and a peptide lactone structure by extensive NMR and MS analyses. In addition, the absolute configuration of 1 was established by Marfey's and modified Mosher's methods.

引用

页码：1344 / 1347

页数：4

共 14 条

[1]

[Anonymous], 1989, U.S. Patent, Patent No. [4,874,745, 4874745]

[2]

[Anonymous], 1996, Japan Patent, Patent No. [96,151,394, 96151394]

[3] Marfey's reagent for chiral amino acid analysis:: A review [J].

Bhushan, R ;

Brückner, H .

AMINO ACIDS, 2004, 27 (3-4) :231-247

[4] METABOLIC PRODUCTS OF MICROORGANISMS .183. IMACIDIN, A NEW PEPTIDE ANTIBIOTIC FROM STREPTOMYCES-OLIVACEUS [J].

BRECHTFISCHER, A ;

ZAHNER, H ;

LAATSCH, H .

ARCHIVES OF MICROBIOLOGY, 1979, 122 (03) :219-229

[5] Constant time HMBC (CT-HMBC), a new HMBC technique useful for improving separation of cross peaks [J].

Furihata, K ;

Seto, H .

TETRAHEDRON LETTERS, 1998, 39 (40) :7337-7340

[6] METABOLIC PRODUCTS OF MICROORGANISMS .134. STENOTHRICIN, A NEW INHIBITOR OF BACTERIAL CELL-WALL SYNTHESIS [J].

HASENBOHLER, A ;

KNEIFEL, H ;

KONIG, WA ;

ZAHNER, H ;

ZEILER, HJ .

ARCHIVES OF MICROBIOLOGY, 1974, 99 (04) :307-321

[7]

Hayakawa M., 1989, Actinomycetologica, V3, P95, DOI [10.3209/saj.395, DOI 10.3209/SAJ.3_]

[8] A new angucycline and a new butenolide isolated from lichen-derived Streptomyces spp. [J].

Motohashi, Keiichiro ;

Takagi, Motoki ;

Yamamura, Hideki ;

Hayakawa, Masayuki ;

Shin-ya, Kazuo .

JOURNAL OF ANTIBIOTICS, 2010, 63 (09) :545-548

[9] Tetrapeptides Possessing a Unique Skeleton, JBIR-34 and JBIR-35, Isolated from a Sponge-Derived Actinomycete, Streptomyces sp Sp080513GE-23 [J].

Motohashi, Keiichiro ;

Takagi, Motoki ;

Shin-ya, Kazuo .

JOURNAL OF NATURAL PRODUCTS, 2010, 73 (02) :226-228

[10] HIGH-FIELD FT NMR APPLICATION OF MOSHER METHOD - THE ABSOLUTE-CONFIGURATIONS OF MARINE TERPENOIDS [J].

OHTANI, I ;

KUSUMI, T ;

KASHMAN, Y ;

KAKISAWA, H .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1991, 113 (11) :4092-4096

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