Visualization of protein fold space via nonmetric multidimensional scaling

被引：413

作者：

Xu, Q ^{[1
]}

机构：

[1] Tsinghua Univ, Dept Biol Sci & Biotechnol, State Key Lab Biomembrane & Membrane Biotechnol, Beijing 100084, Peoples R China

来源：

PROTEIN AND PEPTIDE LETTERS | 2005年 / 12卷 / 05期

关键词：

protein fold; protein fold space; nonmetric multidimensional scaling; structure alignment;

D O I：

10.2174/0929866054395257

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

In this paper, a 3D map of protein fold space was produced using Dali structure alignment and nonmetric multidimensional scaling. The fold space comprises four radial clusters, which correspond to the four classes of SCOP. The overall structure of the protein fold space is largely determined by three factors: secondary structure composition, topology of beta sheet, and domain size.

引用

页码：473 / 475

页数：3

共 21 条

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