Case report of rapidly progressive proliferative verrucous leukoplakia and a proposal for aetiology in mainland China

被引:9
作者
Ge, Lin [2 ]
Wu, Yun [2 ]
Wu, Lan-yan [3 ]
Zhang, Lin [2 ]
Xie, Bing [2 ]
Zeng, Xin [1 ]
Lin, Mei [1 ]
Zhou, Hong-mei [1 ]
机构
[1] Sichuan Univ, Dept Oral Med, W China Hosp Stomatol, Chengdu 610064, Sichuan, Peoples R China
[2] Sichuan Univ, State Key Lab Oral Dis, Chengdu 610064, Sichuan, Peoples R China
[3] Sichuan Univ, Dept Oral Pathol, W China Coll Stomatol, Chengdu 610064, Sichuan, Peoples R China
基金
中国国家自然科学基金;
关键词
EPSTEIN-BARR-VIRUS; HUMAN-PAPILLOMAVIRUS; LONG-TERM; PVL;
D O I
10.1186/1477-7819-9-26
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Proliferative verrucous leukoplakia (PVL) is a rare oral leukoplakia and has four features such as chronic proliferation, multiple occurrences, refractoriness to treatment and high rate of malignant transformation. As mentioned above, most PVL cases processed to malignancy over many years, sometimes 20 years. However, this report described a case of rapid progress, which had malignant transformation in a short period. Additionally, the aetiology of PVL was discussed and immunity was proposed as the possible cause.
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页数:4
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