Nanoparticles for highly efficient multiphoton fluorescence bioimaging

被引:74
作者
Martinez Maestro, Laura [1 ]
Martin Rodriguez, Emma [1 ]
Vetrone, Fiorenzo [2 ]
Naccache, Rafik [2 ]
Loro Ramirez, Hector [3 ]
Jaque, Daniel [1 ]
Capobianco, John A. [2 ]
Garcia Sole, Jose [1 ]
机构
[1] Univ Autonoma Madrid, Dept Fis Mat, GIEL, Madrid 8049, Spain
[2] Concordia Univ, Dept Chem & Biochem, Montreal, PQ H4B 1R6, Canada
[3] Univ Nacl Ingn, Fac Ciencias, Lima, Peru
基金
加拿大自然科学与工程研究理事会;
关键词
UP-CONVERSION LUMINESCENCE; EXCITATION CROSS-SECTIONS; 2-PHOTON LUMINESCENCE; GOLD NANORODS; QUANTUM DOTS; IN-VITRO; CELLS; LANTHANIDE; NANOCRYSTALS; MICROSCOPY;
D O I
10.1364/OE.18.023544
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
In this paper, we demonstrate for the first time that the new class of fluoride-based inorganic upconverting nanoparticles, NaYF4:Er3+, Yb3+, are the most efficient multiphoton excited fluorescent nanoparticles developed to date. The near-infrared-to-visible conversion efficiency of the aforementioned nanoparticles surpasses that of CdSe quantum dots and gold nanorods, which are the commercially available inorganic fluorescent nanoprobes presently used for multiphoton fluorescence bioimaging. The results presented here open new perspectives for the implementation of fluorescence tomography by multiphoton fluorescence imaging. (C) 2010 Optical Society of America
引用
收藏
页码:23544 / 23553
页数:10
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