A function for subtelomeric DNA in Saccharomyces cerevisiae

被引:0
作者
Barton, AB [1 ]
Su, YP [1 ]
Lamb, J [1 ]
Barber, D [1 ]
Kaback, DB [1 ]
机构
[1] UMDNJ, New Jersey Med Sch, Dept Microbiol & Mol Genet, Int Ctr Publ Hlth,Grad Sch Biomed Sci, Newark, NJ 07101 USA
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中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
The subtelomeric DNA sequences from chromosome I of Saccharomyces cerevisiae are shown to be inherently poor substrates for meiotic recombination. On the basis of these results and prior observations that crossovers near telomeres do not promote efficient meiosis I segregation, we suggest that subtelomeric sequences evolved to prevent recombination from occurring where it cannot promote efficient segregation.
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页码:929 / 934
页数:6
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