Nucleosides and Nucleoside Analogues as Emerging Antiviral Drugs

被引:6
|
作者
Elzagheid, Mohamed Ibrahim [1 ]
机构
[1] Jubail Ind Coll, Dept Chem & Proc Engn Technol, Jubail Ind City 31961, Saudi Arabia
关键词
Antiviral drugs; applications; mode of action; nucleoside analogous; structure; toxicity; viral diseases; CHRONIC HEPATITIS-B; TENOFOVIR DISOPROXIL FUMARATE; TREATMENT-NAIVE PATIENTS; ACTIVE ANTIRETROVIRAL THERAPY; LONG-TERM EFFICACY; ADEFOVIR DIPIVOXIL; MITOCHONDRIAL TOXICITY; TOPICAL TREATMENT; SAFETY; ENTECAVIR;
D O I
10.2174/1570193X17999200820163234
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Nucleosides and their analogues have been in use for many years and have become essen-tial for treating patients with viral infections. Many additional nucleoside drugs have been approved over the past decades. This strongly demonstrates how important these compounds are and the cru-cial role they play. Given that a significant amount of research and literature has been documented regarding nucleoside analogues, this review article mainly focuses on nucleosides and nucleoside an-alogues that have proven to play a significant role in the treatment of known viral infections. This ar-ticle covers the names, structures, applications, toxicity, and mode of action of relevant nucleoside analogues.
引用
收藏
页码:672 / 679
页数:8
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