Precision Medicine and Targeted Therapies in Breast Cancer

被引：43
|
作者：
Greenwalt, Ian [1 ]
Zaza, Norah [2 ]
Das, Shibandri [1 ]
Li, Benjamin D. [3 ]
机构：
[1] Case Western Reserve Univ, Univ Hosp Cleveland Med Ctr, MetroHlth Hosp, Stokes Vet Adm Hosp, Cleveland, OH 44106 USA
[2] Case Western Reserve Univ, Cleveland, OH 44106 USA
[3] Case Western Reserve Univ, MetroHlth Syst, Canc Care Pavil,Suite C2100,2500 MetroHlth Dr, Cleveland, OH 44109 USA
来源：
SURGICAL ONCOLOGY CLINICS OF NORTH AMERICA | 2020年 / 29卷 / 01期
关键词：
Breast cancer; Precision medicine; Targeted therapy; Endocrine therapy; HER2; Multigene array; Genomics; Radiomics; MOLECULAR SUBTYPES; COMBINATION; TAMOXIFEN; LETROZOLE; WOMEN;
D O I：
10.1016/j.soc.2019.08.004
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Precision medicine and targeted therapies have a long history in the treatment of breast cancer and continue to show promise for further specialized and individualized care for this disease. From the discovery of endocrine and HER2 targeted therapies, to multigene arrays in chemotherapy for more specific patient selection, to radiomics and genetic sub typing, targeted therapies and precision medicine continue to push the management of breast cancer toward more individualized care. This article describes the foundation and future of targeted therapy and precision medicine in breast cancer.
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收藏
页码：51 / +
页数：13
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