The development of asthma in wheezing infants with Chlamydia pneumoniae infection

被引：11

作者：

Zaitsu, Masafumi ^{[1
]}

机构：

[1] Saga Univ, Dept Pediat, Fac Med, Saga 8498501, Japan

来源：

JOURNAL OF ASTHMA | 2007年 / 44卷 / 07期

关键词：

asthma; Chlamydia pneumoniae; specific IgM antibody; infant wheezing;

D O I：

10.1080/02770900701537115

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

Chlamydia pneumoniae infection might play a role in the pathology of asthma, but its role in infantile asthma remains obscure. The presence of Chlamydia pneumoniae was serologically determined in wheezing infants who were then re-examined 1-year later to determine whether or not asthma is associated with this type of infection. Wheezing infants progressed to asthma more frequently after infection with Chlamydia pneumoniae than those who were not infected. These findings suggested that Chlamydia pneumoniae infection triggers asthma in wheezy infants.

引用

页码：565 / 568

页数：4

共 39 条

[1] Toll-like receptor 2 ligands activate human basophils for both IgE-dependent and IgE-independent secretion [J].

Bieneman, AP ;

Chichester, KL ;

Chen, YH ;

Schroeder, JT .

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2005, 115 (02) :295-301

[2] Increased frequency of detection of Chiamydophila pneumoniae in asthma [J].

Biscione, GL ;

Corne, J ;

Chauhan, AJ ;

Johnston, SL .

EUROPEAN RESPIRATORY JOURNAL, 2004, 24 (05) :745-749

[3] Atypical pathogens and respiratory tract infections [J].

Blasi, F .

EUROPEAN RESPIRATORY JOURNAL, 2004, 24 (01) :171-181

[4] Chlamydial heat shock protein 60 activates macrophages and endothelial cells through toll-like receptor 4 and MD2 in a MyD88-dependent pathway [J].

Bulut, Y ;

Faure, E ;

Thomas, L ;

Karahashi, H ;

Michelsen, KS ;

Equils, O ;

Morrison, SG ;

Morrison, RP ;

Arditi, M .

JOURNAL OF IMMUNOLOGY, 2002, 168 (03) :1435-1440

[5] Chlamydia pneumoniae and atherosclerosis:: Links to the disease process [J].

Byrne, GI ;

Kalayoglu, MV .

AMERICAN HEART JOURNAL, 1999, 138 (05) :S488-S490

[6] DETECTION OF ANTI-CHLAMYDIA PNEUMONIAE IGE IN CHILDREN WITH REACTIVE AIRWAY DISEASE [J].

EMRE, U ;

SOKOLOVSKAYA, N ;

ROBLIN, PM ;

SCHACHTER, J ;

HAMMERSCHLAG, MR .

JOURNAL OF INFECTIOUS DISEASES, 1995, 172 (01) :265-267

[7] THE ASSOCIATION OF CHLAMYDIA-PNEUMONIAE INFECTION AND REACTIVE AIRWAY DISEASE IN CHILDREN [J].

EMRE, U ;

ROBLIN, RM ;

GELLING, M ;

DUMORNAY, W ;

RAO, M ;

HAMMERSCHLAG, MR ;

SCHACHTER, J .

ARCHIVES OF PEDIATRICS & ADOLESCENT MEDICINE, 1994, 148 (07) :727-732

[8] Prevalence of Chlamydia pneumoniae in healthy children and in children with respiratory tract infections [J].

Falck, G ;

Gnarpe, J ;

Gnarpe, H .

PEDIATRIC INFECTIOUS DISEASE JOURNAL, 1997, 16 (06) :549-554

[9] Increased frequency of Chlamydia pneumoniae antibodies in patients with asthma [J].

Gencay, M ;

Rüdiger, JJ ;

Tamm, M ;

Solér, M ;

Perruchoud, AP ;

Roth, M .

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2001, 163 (05) :1097-1100

[10] EVIDENCE THAT CHLAMYDIA-PNEUMONIAE CAUSES PNEUMONIA AND BRONCHITIS [J].

GRAYSTON, JT ;

ALDOUS, MB ;

EASTON, A ;

WANG, SP ;

KUO, CC ;

CAMPBELL, LA ;

ALTMAN, J .

JOURNAL OF INFECTIOUS DISEASES, 1993, 168 (05) :1231-1235

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