Long-term follow-up study of clear cell papulosis

被引：21

作者：

Tseng, Fang-Wen ^{[1
]}

Kuo, Tseng-Tong ^{[2
,3
]}

Lu, Pei-Hsuan ^{[1
,3
]}

Chan, Heng-Leong ^{[4
]}

Chan, Ming-Jing ^{[1
,3
]}

Hui, Rosaline Chung-Yee ^{[1
,3
]}

机构：

[1] Chang Gung Mem Hosp, Dept Dermatol, Taipei 10591, Taiwan

[2] Chang Gung Mem Hosp, Dept Pathol, Taipei 10591, Taiwan

[3] Chang Gung Univ, Coll Med, Taipei, Taiwan

[4] Sutein Clin, Dept Dermatol, Taipei, Taiwan

来源：

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY | 2010年 / 63卷 / 02期

关键词：

clear cell papulosis; clear cells of Toker; extramammary Paget disease; long-term follow-up; milk line; EXTRAMAMMARY PAGETS-DISEASE; TOKER CELLS; PRECURSORS; SKIN; LINK;

D O I：

10.1016/j.jaad.2009.08.056

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Background: Clear cell papulosis (CCP) was described as a new entity in 1987. Since then, only case reports or small case series have appeared in the literature and the long-term outcome of CCP remains unknown. Objectives: The aim of this study was to review cases of CCP diagnosed at our institution and to investigate their outcome. Methods: Nineteen patients given a diagnosis of CCP more than 6 years previously were identified. Their medical records and histopathologic findings were reviewed. Results: With a median follow-up duration of 11.5 years, regression of skin lesions was observed in 85.7% of patients. Persistence of skin lesions 11.5 years after diagnosis was confirmed histopathologically in one case, with a reduction in clear cell density. Limitations: Retrospective nature of the study is a limitation. Conclusion: No treatment is necessary for CCP because the skin lesions are asymptomatic and most patients experience at least partial regression. (J Am Acad Dermatol 2010;63:266-73.)

引用

页码：266 / 273

页数：8

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