Introduction. - Indoor moulds can be responsible for respiratory pathologies in at-risk subjects (allergy...). The objective is to characterise the moulds in an indoor environment to prevent the risks of exposure. Methodology. - This is a descriptive study of 432 samples (Air, Surface and Dust) taken from two sites in Abidjan, Ivory Coast from February to July 2019. Results. - The samples allowed the isolation of 120 species on site A and 1190 species on site B. The species recorded are Aspergillus 39.39%, Penicillium 16.80%, Fusarium 8.55%, Curvularia 1.45%, Rhizomucor 1.22%, Mucor 1.15%, Aureobasidium 0.15%, Scytalidium 0.08% and other species 31.22% with colonisation rates of 720 CFU/24 hours for air sampling, 21.10(7) CFU/dm(2) for surface sampling and 4.10(6) CFU/dm(2) for dust sampling. Conclusion. - This study will have made it possible to catalogue the moulds isolated on (02) sites in Abidjan, which together with the list of moulds from other studies in Cote d'Ivoire can be used as a local reference tool for health surveillance. (C) 2021 Elsevier Masson SAS. All rights reserved.