NeuO: a Fluorescent Chemical Probe for Live Neuron Labeling

被引：66

作者：

Er, Jun Cheng ^{[1
]}

Leong, Cheryl ^{[2
]}

Teoh, Chai Lean ^{[2
]}

Yuan, Qiang ^{[3
]}

Merchant, Paolomi ^{[4
]}

Dunn, Matthew ^{[4
]}

Sulzer, David ^{[5
,6
]}

Sames, Dalibor ^{[4
]}

Bhinge, Akshay ^{[7
]}

Kim, Dongyoon ^{[8
]}

Kim, Seong-Min ^{[8
]}

Yoon, Myung-Han ^{[8
]}

Stanton, Lawrence W. ^{[7
]}

Je, Shawn H. ^{[3
]}

Yun, Seong-Wook ^{[2
]}

Chang, Young-Tae ^{[1
,2
]}

机构：

[1] Natl Univ Singapore, Dept Chem, Singapore 117543, Singapore

[2] Agcy Sci Technol & Res, Singapore BioImaging Consortium, Singapore 138667, Singapore

[3] Natl Univ Singapore, Duke NUS Grad Med Sch, Singapore 169857, Singapore

[4] Columbia Univ, Dept Chem, New York, NY 10027 USA

[5] Columbia Univ, Dept Neurol, New York, NY 10032 USA

[6] Columbia Univ, Dept Psychiat, New York, NY 10032 USA

[7] Agcy Sci Technol & Res, Genome Inst Singapore, Singapore 138672, Singapore

[8] Gwangju Inst Sci & Technol, Kwangju 500712, South Korea

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2015年 / 54卷 / 08期

关键词：

BODIPY; fluorescent probes; imaging agents; live neurons; MICROGLIA;

D O I：

10.1002/anie.201408614

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

To address existing limitations in live neuron imaging, we have developed NeuO, a novel cell-permeable fluorescent probe with an unprecedented ability to label and image live neurons selectively over other cells in the brain. NeuO enables robust live neuron imaging and isolation invivo and invitro across species; its versatility and ease of use sets the basis for its development in a myriad of neuronal targeting applications.

引用

页码：2442 / 2446

页数：5

共 50 条

[1] NeuO for Neuronal Labeling in Zebrafish
Teoh, Chai Lean
Er, Jun Cheng
Mukherjee, Parag
Chang, Young-Tae
TOMOGRAPHY, 2015, 1 (01) : 30 - 36
[2] Fast neuronal labeling in live tissue using a biocytin conjugated fluorescent probe
Harslof, Mads
Muller, Felix C.
Rohrberg, Julie
Rekling, Jens C.
JOURNAL OF NEUROSCIENCE METHODS, 2015, 253 : 101 - 109
[3] Advances in Synthetic Fluorescent Probe Labeling for Live-Cell Imaging in Plants
Yagi, Noriyoshi
Yoshinari, Akira
Iwatate, Ryu J.
Isoda, Reika
Frommer, Wolf B.
Nakamura, Masayoshi
PLANT AND CELL PHYSIOLOGY, 2021, 62 (08) : 1259 - 1268
[4] Chemical biology-based approaches on fluorescent labeling of proteins in live cells
Jung, Deokho
Min, Kyoungmi
Jung, Juyeon
Jang, Wonhee
Kwon, Youngeun
MOLECULAR BIOSYSTEMS, 2013, 9 (05) : 862 - 872
[5] Fluorescent Labeling of Glycogen in Live Cells
Hendrix, Wayne
Danielsen, Carl
Parker, Glendon
DIABETES, 2010, 59 : A413 - A413
[6] A hydrogen sulfide triggered self-immolative fluorescent probe for lysosome labeling in live cells
Velusamy, Nithya
Thirumalaivasan, Natesan
Bobba, Kondapa Naidu
Wu, Shu-Pao
Bhuniya, Sankarprasad
NEW JOURNAL OF CHEMISTRY, 2018, 42 (03) : 1590 - 1594
[7] Mitochondrial Labeling with Mulberrin-Cy3: A New Fluorescent Probe for Live Cell Visualization
Yuan, Gangxiang
Luo, Yiwei
Qian, Peng
He, Ningjia
BIOSENSORS-BASEL, 2024, 14 (09):
[8] A π-Stacking Based Fluorescent Probe for Labeling of Flavin Analogues in Live Cells through Unusual FRET Process
Biswas, Shayeri
Sarkar, Sourav
Shil, Anushree
Demina, Tatiana S.
Ahn, Kyo Han
Bhuniya, Sankarprasad
ANALYTICAL CHEMISTRY, 2022, 94 (08) : 3494 - 3500
[9] A novel fluorescent probe for selective detection of thiols in acidic solutions and labeling of acidic organelles in live cells
Song, Qin-Hua
Wu, Qing-Qing
Liu, Chang-Hui
Du, Xiao-Jiao
Guo, Qing-Xiang
JOURNAL OF MATERIALS CHEMISTRY B, 2013, 1 (04) : 438 - 442
[10] A novel fluorescent probe for selective labeling of histidine
Li, XH
Ma, HM
Nie, LH
Sun, M
Xiong, SX
ANALYTICA CHIMICA ACTA, 2004, 515 (02) : 255 - 260

← 1 2 3 4 5 →