Comparison of the distributions of neuropeptide Y-, tyrosine hydroxylase-, and tryptophan hydroxylase-expressing neurons in the hypothalamic arcuate nucleus

被引：0
作者：
Vanhatalo, S
机构：
[1] Univ Helsinki, Dept Anat, Inst Biomed, Helsinki 00014, Finland
[2] Univ Helsinki Hosp, Hosp Children & Adolescents, Unit Child Neurol, Helsinki, Finland
来源：
NUTRITIONAL NEUROSCIENCE | 2000年 / 3卷 / 01期
关键词：
serotonin; neuropeptide Y; tyrosine hydroxylase; tryptophan hydroxylase; hypothalamus; arcuate nucleus;
D O I：
10.1080/1028415X.2000.11747299
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
Several levels of interactions between serotonin and neuropeptide Y (NPY) have been proposed in the hypothalamic control of food intake. This study aimed at elucidating-the anatomical relationship between the NPY-expressing neurons and the newly characterized neuronal population of tryptophan hydroxylase (TpH)-expressing (serotonin synthesizing enzyme) neurons in the hypothalamic arcuate nucleus. In addition, their distribution was compared to that of tyrosine hydroxylase (TH), the dopamine synthesizing enzyme. No co-localization of NPY and TpH, or NPY and TH was found in the arcuate nucleus either in intact or in colchicine-treated animals. These results suggest that there is likely no functional cotransmission between these transmitter systems in an intact arcuate nucleus.
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页码：11 / 17
页数：7
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