New Acrylamide and Oxazolidin Derivatives from a Termite-Associated Streptomyces sp.

被引:1
作者
Bi, Shu Feng [1 ]
Li, Fang [1 ]
Song, Yong Chun [1 ]
Tan, Ren Xiang [1 ]
Ge, Hui Ming [1 ]
机构
[1] Nanjing Univ, Inst Funct Biomol, State Key Lab Pharmaceut Biotechnol, Nanjing 210093, Peoples R China
关键词
2-formylpyrrole-4-acrylamide; dihydrostreptazolin; structure elucidation; cytotoxic activity; antimicrobial activity;
D O I
暂无
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Two new compounds, named 2-formylpyrrole-4-acrylamide (1) and dihydrostreptazolin (2) were isolated from the fermentation broth of BY-4, an actinomycetes residing in the gut of Odontotermes formosanus. The structures of 1 and 2 were elucidated by extensive spectral analysis (H-1, C-13, 2D NMR, and HR-ESIMS). The isolated compounds were assayed for cytotoxic and antimicrobial activities.
引用
收藏
页码:353 / 355
页数:3
相关论文
共 9 条
[1]  
Ahmed L, 2010, J NAT PRODUCTS, V73, P1164
[2]   In vitro activities of the new antifungal triazole SCH 56592 against common and emerging yeast pathogens [J].
Barchiesi, F ;
Arzeni, D ;
Fothergill, AW ;
Di Francesco, LF ;
Caselli, F ;
Rinaldi, MG ;
Scalise, G .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2000, 44 (01) :226-229
[3]   Marinomycins A-D, antitumor-antibiotics of a new structure class from a marine actinomycete of the recently discovered genus "Marinispora" [J].
Kwon, HC ;
Kauffman, CA ;
Jensen, PR ;
Fenical, W .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2006, 128 (05) :1622-1632
[4]   STRUCTURE OF SIBIROMYCIN [J].
MESENTSEV, AS ;
KULJAEVA, VV ;
RUBASHEVA, LM .
JOURNAL OF ANTIBIOTICS, 1974, 27 (11) :866-873
[5]   Culture and manipulation of insect facultative symbionts [J].
Pontes, Mauricio H. ;
Dale, Colin .
TRENDS IN MICROBIOLOGY, 2006, 14 (09) :406-412
[6]   POROTHRAMYCIN, A NEW ANTIBIOTIC OF THE ANTHRAMYCIN GROUP - PRODUCTION, ISOLATION, STRUCTURE AND BIOLOGICAL-ACTIVITY [J].
TSUNAKAWA, M ;
KAMEI, H ;
KONISHI, M ;
MIYAKI, T ;
OKI, T ;
KAWAGUCHI, H .
JOURNAL OF ANTIBIOTICS, 1988, 41 (10) :1366-1373
[7]   A STUDY OF SOME VARIABLES IN A TETRAZOLIUM DYE (MTT) BASED ASSAY FOR CELL-GROWTH AND CHEMOSENSITIVITY [J].
TWENTYMAN, PR ;
LUSCOMBE, M .
BRITISH JOURNAL OF CANCER, 1987, 56 (03) :279-285
[8]   X-Ray Absorption Spectroscopy of Cuprous-Thiolate Clusters in Saccharomyces cerevisiae Metallothionein [J].
Zhang, Limei ;
Pickering, Ingrid J. ;
Winge, Dennis R. ;
George, Graham N. .
CHEMISTRY & BIODIVERSITY, 2008, 5 (10) :2042-2049
[9]   Unprecedented immunosuppressive polyketides from Daldinia eschscholzii, a mantis-associated fungus [J].
Zhang, Ying Lao ;
Ge, Hui Ming ;
Zhao, Wei ;
Dong, Hao ;
Xu, Qiang ;
Li, Shu Hita ;
Li, Jing ;
Zhang, Jie ;
Song, Yong Chun ;
Tan, Ren Xiang .
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2008, 47 (31) :5823-5826