Probable Vanishing White Matter Disease: A Case Report and Literature Review

被引：5

作者：

Deginet, Endayen ^{[1
]}

Tilahun, Robel ^{[2
]}

Bishaw, Solomon ^{[3
]}

Eshetu, Konjit ^{[2
]}

Moges, Ayalew ^{[4
]}

机构：

[1] Dire Dawa Univ, Coll Hlth Sci, Sch Med, Dept Pediat & Child Hlth, Dire Dawa, Ethiopia

[2] Haramaya Univ, Coll Hlth Sci, Sch Med, Dept Pediat & Child Hlth, Harar, Ethiopia

[3] Haramaya Univ, Coll Hlth Sci, Dept Radiol, Harar, Ethiopia

[4] Addis Ababa Univ, Coll Hlth Sci, Sch Med, Dept Pediat & Child Hlth, Addis Ababa, Ethiopia

来源：

ETHIOPIAN JOURNAL OF HEALTH SCIENCES | 2021年 / 31卷 / 06期

关键词：

Vanishing White Matter Disease; Child; Ethiopia;

D O I：

10.4314/ejhs.v31i6.28

中图分类号：

R19 [保健组织与事业（卫生事业管理）];

学科分类号：

摘要：

BACKGROUND: Vanishing white matter disease is one of the most prevalent inherited childhood leukoencephalopathies. The disease is characterized by chronic, progressive and episodic deterioration with ataxia and spasticity. CASE PRESENTATION: Here, we report a 15-month-old female child from Dire-Dawa, eastern part of Ethiopia, who presented with regression of developmental milestones and truncal ataxia since her age of 11 months following a febrile illness that occurred one month earlier. Magnetic resonance imaging of brain is suggestive of vanishing white matter disease. CONCLUSIONS: We believe this case report will increase curiosity, awareness and knowledge of health professionals in Ethiopia and sub-Saharan Africa working with children in early consideration and the diagnosis of the disease.

引用

页码：1307 / 1310

页数：4

共 5 条

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