Formal dual C(sp2)-H cross-dehydrogenative C-O bond formation to construct highly functionalized diaryl ethers with O2

被引：5

作者：

Bashir, Muhammad Adnan ^{[1
]}

Tang, Langyu ^{[1
]}

Li, Longjie ^{[1
]}

Yu, Huaibin ^{[1
]}

Yao, Weijun ^{[2
]}

Wu, Guojiao ^{[1
]}

Zhong, Fangrui ^{[1
]}

机构：

[1] Huazhong Univ Sci & Technol HUST, Hubei Engn Res Ctr Biomat & Med Protect Mat, Sch Chem & Chem Engn, Hubei Key Lab Bioinorgan Chem & Mat Med, 1037 Luoyu Rd, Wuhan 430074, Peoples R China

[2] Zhejiang Sci Tech Univ, Dept Chem, Hangzhou, Peoples R China

来源：

ORGANIC CHEMISTRY FRONTIERS | 2022年 / 9卷 / 08期

基金：

中国国家自然科学基金;

关键词：

CATALYTIC AEROBIC FUNCTIONALIZATION; SILYL ENOL ETHERS; COUPLING REACTIONS; ORTHO-QUINONES; PRIMARY AMINES; BIARYL ETHER; ARYL HALIDES; PHENOLS; COPPER; OXIDATION;

D O I：

10.1039/d1qo01942b

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A formal dual C(sp(2))-H cross-dehydrogenative C-O bond formation between phenols and N-substituted naphthylamines to expediently assemble diversely functionalized diaryl ethers bearing hydroxyl and amino functionalities with excellent atom and step economy was developed under mild conditions. The reaction features three C-H cleavages and three C-O bond formations in one pot. In addition a rare C(sp(2))-O bond formation rather than the conventional C-C bond formation took place by addition to a carbonyl O atom of the in situ generated ortho-quinone.

引用

页码：2249 / 2255

页数：7

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