N-{3-[2-(4-Fluorophenoxy)ethyl]-2,4-dioxo-1,3-diazaspiro[4.5]decan-7-yl}-4-methylbenzamide

被引：0
|
作者：
Vinduvahini, M. [2 ]
Saha, Binoy Krishna [3 ]
Mahalakhmi [1 ]
Revanasiddappa, H. D. [4 ]
Devarajegowda, H. C. [1 ]
机构：
[1] Univ Mysore, Dept Phys, Yuvarajas Coll, Constituent Coll, Mysore 570005, Karnataka, India
[2] Sri D Devaraja Urs Govt First Grade Coll, Dept Phys, Hunsur 571105, Karnataka, India
[3] Pondicherry Univ, Dept Chem, Pondicherry 605014, India
[4] Univ Mysore, Dept Studies Chem, Mysore 570006, Karnataka, India
来源：
ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE | 2011年 / 67卷
关键词：
DERIVATIVES; INHIBITORS;
D O I：
10.1107/S1600536811017946
中图分类号：
O7 [晶体学];
学科分类号：
0702 ; 070205 ; 0703 ; 080501 ;
摘要：
In the title compound, C24H26FN3O4, the two aromatic rings form a dihedral angle of 88.81 (15)degrees. The cyclohexane ring adopts a chair conformation and the five-membered ring is essentially planar, with a maximum deviation from planarity of 0.041 (2) A. The crystal structure displays intermolecular C-H...O and N-H...O hydrogen bonds.
引用
收藏
页码：O1440 / U929
页数：13
相关论文
共 37 条
  • [31] (E)-N-(3-(1-(2-(4-(2,2,2-Trifluoroacetamido)benzoyl)hydrazono)ethyl)phenyl)nicotinamide: A Novel Pyridine Derivative for Inhibiting Vascular Endothelial Growth Factor Receptor-2: Synthesis, Computational, and Anticancer Studies
    Yousef, Reda G.
    Elkady, Hazem
    Elkaeed, Eslam B.
    Gobaara, Ibraheem M. M.
    Al-ghulikah, Hanan A.
    Husein, Dalal Z.
    Ibrahim, Ibrahim M.
    Metwaly, Ahmed M.
    Eissa, Ibrahim H.
    MOLECULES, 2022, 27 (22):
  • [32] Discovery of 2-(4-Substituted-piperidin/piperazine-1-yl)-N-(5-cyclopropyl-1H-pyrazol-3-yl)-quinazoline-2,4-diamines as PAK4 Inhibitors with Potent A549 Cell Proliferation, Migration, and Invasion Inhibition Activity
    Wu, Tianxiao
    Pang, Yu
    Guo, Jing
    Yin, Wenbo
    Zhu, Mingyue
    Hao, Chenzhou
    Wang, Kai
    Wang, Jian
    Zhao, Dongmei
    Cheng, Maosheng
    MOLECULES, 2018, 23 (02):
  • [33] Discovery of 6-(2-(dimethylamino)ethyl)-N-(5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole-6-yl)pyrimidin-2-yl)-5,6,7,8-tetrahydro-1,6-naphthyridin-2-amine as a highly potent cyclin-dependent kinase 4/6 inhibitor for treatment of cancer
    Shi, Chen
    Wang, Qian
    Liao, Xuemei
    Ge, Hui
    Huo, Guoyong
    Zhang, Leduo
    Chen, Na
    Zhai, Xiong
    Hong, Yuan
    Wang, Li
    Han, Yanan
    Xiao, Wenbo
    Wang, Zhe
    Shi, Weijun
    Mao, Yu
    Yu, Jianxin
    Xia, Guangxin
    Liu, Yanjun
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 178 : 352 - 364
  • [34] Discovery of N-(1-(3-(4-phenoxyphenyl)-1,2,4-oxadiazol-5-yl)ethyl)acetamides as novel acetyl-CoA carboxylase 2 (ACC2) inhibitors with peroxisome proliferator-activated receptor α/δ (PPARα/δ) dual agonistic activity
    Okazaki, Shogo
    Noguchi-Yachide, Tomomi
    Sakai, Taki
    Ishikawa, Minoru
    Makishima, Makoto
    Hashimoto, Yuichi
    Yamaguchi, Takao
    BIOORGANIC & MEDICINAL CHEMISTRY, 2016, 24 (21) : 5258 - 5269
  • [35] Selectivity of N-Aroyl-N′-arylthioureas towards 2-(1,3-Dioxo-1H-inden-2(3H)-ylidene)malononitrile. New Synthesis of (Z)-N-((E)-4-Amino-1-aryl-5-cyano-6-oxo-1H-indeno[1,2-d][1,3]-thiazepin-2(6H)-ylidene)-4-arylamides of Antitumor and Antioxidant Activities
    Aly, Ashraf A.
    Brown, Alan B.
    Ramadan, Mohamed
    Abdel-Aziz, Mohamed
    Abuo-Rahma, Gamal El-Din A. A.
    Radwan, Mohamed F.
    Gamal-Eldeen, Amira M.
    JOURNAL OF HETEROCYCLIC CHEMISTRY, 2010, 47 (03) : 503 - 508
  • [36] Design, synthesis of novel (Z)-2-(3-(4-((3-benzyl-2,4dioxothiazolidin-5-ylidene)methyl)-1-phenyl-1H-pyrazol-3-yl) phenoxy)-N-arylacetamide derivatives: Evaluation of cytotoxic activity and molecular docking studies
    Kolluri, Prashanth Kumar
    Gurrapu, Nirmala
    Subhashini, N. J. P.
    Putta, Shravani
    Singh, Surya Sathyanarayana
    Vani, Tamalapakula
    Manga, Vijjulatha
    JOURNAL OF MOLECULAR STRUCTURE, 2020, 1202
  • [37] Synthesis and Characterization of 2-((4R,4aR,5aS,6S)-1,3-dioxo-3,3a,4,4a,5,5a,6,6a-octahydro-4,6-ethenocyclopropa[f]isoindol-2(1H)-yl)-N-(Substituted Phenyl) Acetamides Derivatives Anticipated to Inhibit HIV-1 Activity
    Alsamarrai, Abdulmajeed S. H.
    Abdulla, Noor H.
    Aldoori, Malath Khalaf
    INTERNATIONAL JOURNAL OF PHARMACEUTICAL AND PHYTOPHARMACOLOGICAL RESEARCH, 2018, 8 (05): : 7 - 11
1234