Exotoxin secretion: Getting out to find the way in

被引：8

作者：

Bischofberger, Mirko ^{[1
]}

van der Goot, F. Gisou ^{[1
]}

机构：

[1] Ecole Polytech Fed Lausanne, Global Hlth Inst, CH-1015 Lausanne, Switzerland

来源：

CELL HOST & MICROBE | 2008年 / 3卷 / 01期

关键词：

D O I：

10.1016/j.chom.2007.12.003

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

During infection, most pathogenic bacteria deliver proteins to the host cell cytoplasm to manipulate host behavior. In this issue of Cell Host & Microbe, Spano and colleagues describe a system where a bacterium produces an exotoxin while inside the host cell. Only after this exotoxin is transported to the mammalian cell surface and secreted into the extracellular milieu can it intoxicate the infected cell or noninfected distant cells.

引用

页码：7 / 8

页数：2