Stereoselective synthesis of the various isomers of 3,4-dideoxy furanoid sugar amino acids with methyl substitution at the C6 position

被引：7

作者：

Chakraborty, TK ^{[1
]}

Sudhakar, G ^{[1
]}

机构：

[1] Indian Inst Chem Technol, Hyderabad 500007, Andhra Pradesh, India

来源：

TETRAHEDRON LETTERS | 2005年 / 46卷 / 25期

关键词：

sugar amino acids; amino acids; peptidomimetics; dipeptide isosteres;

D O I：

10.1016/j.tetlet.2005.04.094

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Various isomers of C6-methyl-containing chiral 3,4-dideoxy furanoid Sugar amino acids were synthesized following a common strategy, in which the C2 and C6 chiral centres were derived from the chiralities of the two starting materials, glyceraldehyde acetonide and N,N-dibenzylalaninal, respectively, and the C5 centre was fixed by standard diastereoselective transformations. (c) 2005 Elsevier Ltd. All rights reserved.

引用

页码：4287 / 4290

页数：4