Transition-Metal-Catalyzed Regioselective C-H Borylation of Pyridines

被引：3

作者：

Sun, Qianlin ^{[1
]}

Luo, Yuncong ^{[1
]}

Xu, Xin ^{[1
]}

机构：

[1] Soochow Univ, Coll Chem Chem Engn & Mat Sci, Key Lab Organ Synth Jiangsu Prov, Suzhou 215123, Peoples R China

来源：

SYNLETT | 2022年 / 33卷 / 20期

基金：

中国国家自然科学基金;

关键词：

borylation; C-H activation; regioselectivity; pyridines; transition metals; IRIDIUM CATALYSTS; FUNCTIONALIZATION; ACTIVATION; ARENES; CONSTRUCTION; QUINOLINES; COMPLEXES;

D O I：

10.1055/a-1890-8375

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The C-H borylation strategy has spurred intense research endeavors due to the high atom- and step-economy it represents and because of the broad range of utilities of the resulting organoboranes. Nevertheless, this powerful transformation has had limited substrate scope and poor regioselectivity when it was applied to Lewis basic substrates (e.g., azines). The basic functionalities in substrates can coordinate to the metal centers, hindering the formation of products. Herein, we provide a brief overview of recent advances in transition-metal-catalyzed regioselective C-H borylation of pyridines. Attention is paid to the latest contributions, which have demonstrated remarkable regioselectivity.

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页码：1961 / 1967

页数：7

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