A practical two-step synthesis of imidazo[1,2-a]pyridines from N-(prop-2-yn-1-yl)pyridin-2-amines

被引：37

作者：

Sucunza, David ^{[1
]}

Samadi, Abdelouahid ^{[1
]}

Chioua, Mourad ^{[1
]}

Silva, Daniel B. ^{[1
,2
]}

Yunta, Cristina ^{[3
]}

Infantes, Lourdes ^{[3
]}

Carmo Carreiras, M. ^{[2
]}

Soriano, Elena ^{[1
]}

Marco-Contelles, Jose ^{[1
]}

机构：

[1] IQOG CSIC, Lab Radicales Libres & Quim Computac, Madrid 28006, Spain

[2] Univ Lisbon, iMed UL, Res Inst Med & Pharmaceut Sci, P-1600083 Lisbon, Portugal

[3] Inst Quim Fis, Madrid 28006, Spain

来源：

CHEMICAL COMMUNICATIONS | 2011年 / 47卷 / 17期

关键词：

CONVENIENT SYNTHESIS; BICYCLIC PYRIDONES; DERIVATIVES; SANDMEYER; IMIDAZOLE; ANALOGS; ALKYNES; ACID;

D O I：

10.1039/c1cc10641d

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The Sandmeyer reaction of differently C-2 substituted N-(prop-2yn-1-ylamino)pyridines is an efficient, mild, new and practical method for the stereospecific synthesis of (E)-exo-halomethylene bicyclic pyridones bearing the imidazo[1,2-a]pyridine heterocyclic ring system.

引用

页码：5043 / 5045

页数：3

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