Effect of Diazocine Bridgehead Modification on the Folding of the Wilcox Molecular Torsion Balance: A View from a Different Angle

被引：14

作者：

Bhayana, Brijesh ^{[2
]}

Ams, Mark R. ^{[1
]}

机构：

[1] Massachusetts Gen Hosp, Wellman Ctr Photomed, Boston, MA 02114 USA

[2] Allegheny Coll, Dept Chem, Meadville, PA 16335 USA

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2011年 / 76卷 / 09期

关键词：

ORTHOGONAL DIPOLAR INTERACTIONS; FACE AROMATIC INTERACTIONS; FUNCTIONAL-GROUP ARRAYS; SYNTHETIC RECEPTORS; BASE ANALOGS; TROGERS BASE; PI-STACKING; CHEMISTRY;

D O I：

10.1021/jo200316t

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Replacing the methano (NCH2N) bridgehead with an ethano (NCH2CH2N) bridgehead affects the conformational equilibrium of the Wilcox molecular torsion balance. With a NCH2CH2N bridgehead, the phenyl and the cyclohexyl esters prefer the out conformation, whereas with the NCH2N bridgehead, they were found to prefer the folded conformation.

引用

页码：3594 / 3596

页数：3

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