Trace alignment and some of its applications

被引：5
|
作者：
Mott, R [1 ]
机构：
[1] Sanger Ctr, Informat Grp, Cambridge CB10 1SA, England
来源：
BIOINFORMATICS | 1998年 / 14卷 / 01期
关键词：
D O I：
10.1093/bioinformatics/14.1.92
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
Motivation: Extra useful information can be extracted form a DNA chromatogram trace, over that contained in the base-called DNA sequence. Many sequencing applications can benefit from examination of these traces. Results: An algorithm, based on dynamic programming, for aligning a DNA chromatogram to a DNA sequence is described and implemented. Its applications to vector clipping, EST alignment and mutation detection are discussed.
引用
收藏
页码：92 / 97
页数：6
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