Liver biopsy in a district general hospital: Changes over two decades

被引:4
作者
Syn, Wing-Kin [1 ]
Bruckner-Holt, Caroline
Farmer, Adam
Howdle, Sarah
Bateman, Jeffrey
机构
[1] Queen Elizabeth Hosp, Liver & Hepatobiliary Unit, Birmingham B15 2TH, W Midlands, England
[2] Princess Royal Hosp, Dept Gastroenterol, Telford TF6 6TF, Shrops, England
[3] City Hosp, Dept Gastroenterol, Birmingham, W Midlands, England
[4] Princess Royal Hosp, Dept Radiol, Telford TF6 6TF, Shrops, England
关键词
complication; district general; indication; liver biopsy; non-alcoholic fatty liver;
D O I
10.3748/wjg.v13.i40.5336
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
AIM: To study liver biopsy practice over two decades in a district general hospital in the United Kingdom. METHODS: We identified all patients who had at least one liver biopsy between 1986 and 2006 from the databases of the radiology and gastroenterology departments. Subjects with incomplete clinical data were excluded from the study. RESULTS: A total of 103 liver biopsies were performed. Clinical data was available for 88 patients, with 95 biopsies. Between 1986 and 1996, 18 (95%) out of the 19 liver biopsies performed were blind and 6 (33%) were for primary biliary cirrhosis. Between 1996 and 2006, 14 (18%) out of 76 biopsies were blind; and the indications were abnormal liver tests (33%), hepatitis C (12%) and targeted-biopsies (11%). Liver biopsies were unhelpful in 5 (5%) subjects. Pain was the most common complication of liver biopsy (5%). No biopsy-related mortality was reported. There was a trend towards more technical failures and complications with the blind biopsy technique. CONCLUSION: Liver biopsies performed in small district hospitals are safe and useful for diagnostic and staging purposes. Abnormal liver tests, non-alcoholic fatty liver disease and targeted biopsies are increasingly common indications. Ultrasound-guided liver biopsies are now the preferred method and are associated with fewer complications. (C) 2007 WJG. All rights reserved.
引用
收藏
页码:5336 / 5342
页数:7
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