Evaluation of the dosimetric consequences of adding a single asymmetric or MLC shaped field to a tangential breast radiotherapy technique

被引:20
作者
Richmond, ND
Turner, RN
Dawes, PJDK
Lambert, GD
Lawrence, GP
机构
[1] Newcastle Gen Hosp, Dept Reg Med Phys, Newcastle Upon Tyne NE4 6BE, Tyne & Wear, England
[2] Newcastle Gen Hosp, No Ctr Canc Treatment, Newcastle Upon Tyne NE4 6BE, Tyne & Wear, England
关键词
radiotherapy; breast cancer; treatment planning; dose inhomogeneity;
D O I
10.1016/S0167-8140(03)00008-2
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Fifteen consecutive patients had standard treatment plans generated using our departmental protocol and two further plans produced using either an asymmetric, or MLC shaped additional field, from each tangential direction. The mean percentage of the PTV receiving over 107% of the isocentre dose was 19.8% for the standard planned patients (95% confidence interval 12.3-27.4%). This was reduced to 6.0% for the asymmetric field technique (95% confidence interval 4.1-8.0%) and 5.3% for the MLC technique (95% confidence interval 2.8-7.7%). These high dose volume reductions were therefore significant at the 95% confidence level. It was also concluded that both alternative planning techniques offer the greatest potential when the standard plan indicated that more than 20% of the PTV would receive greater than 107% of the prescribed dose. Under these circumstances the segmented field techniques led to a reduction of at least 15 percentage points in this figure. It is this group of patients who stand to benefit most from application of these simple additional field techniques. (C) 2003 Elsevier Science Ireland Ltd. All rights reserved.
引用
收藏
页码:165 / 170
页数:6
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