Survival Outcomes in Oropharyngeal Small-Cell Carcinoma Compared With Squamous Cell Carcinoma: A Population-Based Study

Small-cell carcinoma (SmCC) is a neuroendocrine malignant neoplasm that usually occurs in the lungs. Oropharyngeal SmCC is a rare entity, with the current literature limited to case reports and small case series. Many of these reports suggest that it is a highly aggressive disease with dismal outcomes.(1-6) However, it is difficult to draw conclusions about the survival outcomes of oropharyngeal SmCC based on the existing literature. The goal of our study was to evaluate the survival outcomes of oropharyngeal SmCC, compared with squamous cell carcinoma (SqCC).