A simple multiplier to calculate the impact of HDL cholesterol on cardiovascular risk estimation using SCORE

被引:7
作者
Descamps, Olivier S. [1 ,2 ]
Cooney, Marie Therese [3 ]
De Backer, Guy [4 ]
Graham, Ian [3 ]
机构
[1] Hop Jolimont, Ctr Rech Med Jolimont, B-7100 Haine St Paul, Belgium
[2] Hop Jolimont, Dept Med Interne, B-7100 Haine St Paul, Belgium
[3] Adelaide & Meath Hosp, Dept Cardiol, Dublin 24, Ireland
[4] Ghent Univ Hosp, Dept Cardiol, Ghent, Belgium
关键词
SCORE; Cardiovascular risk; Risk assessment; Prevention; HDL cholesterol; Guidelines; GUIDELINES; DISEASE;
D O I
10.1016/j.atherosclerosis.2012.03.035
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The 2011 ESC-EAS guidelines on the management of dyslipidaemias use four separate charts to illustrate the impact of differing HDL cholesterol levels on risk of cardiovascular disease. We developed an easy way to calculate the effects of differing HDL-C levels on risk by deriving HDL and sex specific multipliers and applying these to various reference charts. Of three strategies explored, one based on a low HDL (0.8 mmol/l) reference chart was the simplest and was acceptably accurate. Such an approach simplifies risk estimation by avoiding the need for multiple charts. (C) 2012 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码:564 / 566
页数:3
相关论文
共 4 条
[1]   Estimation of ten-year risk of fatal cardiovascular disease in Europe:: the SCORE project [J].
Conroy, RM ;
Pyörälä, K ;
Fitzgerald, AP ;
Sans, S ;
Menotti, A ;
De Backer, G ;
De Bacquer, D ;
Ducimetière, P ;
Jousilahti, P ;
Keil, U ;
Njolstad, I ;
Oganov, RG ;
Thomsen, T ;
Tunstall-Pedoe, H ;
Tverdal, A ;
Wedel, H ;
Whincup, P ;
Wilhelmsen, L ;
Graham, IM .
EUROPEAN HEART JOURNAL, 2003, 24 (11) :987-1003
[2]   How much does HDL cholesterol add to risk estimation? A report from the SCORE investigators [J].
Cooney, Marie Therese ;
Dudina, Alexandra ;
De Bacquer, Dirk ;
Fitzgerald, Anthony ;
Conroy, Ronan ;
Sans, Susana ;
Menotti, Alessandro ;
De Backer, Guy ;
Jousilahti, Pekka ;
Keil, Ulrich ;
Thomsen, Troels ;
Whincup, Peter ;
Graham, Ian .
EUROPEAN JOURNAL OF CARDIOVASCULAR PREVENTION & REHABILITATION, 2009, 16 (03) :304-314
[3]   European guidelines on cardiovascular disease prevention in clinical practice: Full text [J].
Graham, Ian ;
Atar, Dan ;
Borch-Johnsen, Knut ;
Boysen, Gudrun ;
Burell, Gunilla ;
Cifkova, Renata ;
Dallongeville, Jean ;
De Backer, Guy ;
Ebrahim, Shah ;
Gjelsvik, Bjorn ;
Herrmann-Lingen, Christoph ;
Hoes, Arno ;
Humphries, Steve ;
Knapton, Mike ;
Perk, Joep ;
Priori, Silvia G. ;
Pyorala, Kalevi ;
Reiner, Zeljko ;
Ruilope, Luis ;
Sans-Menendez, Susana ;
Reimer, Wilma Scholte Op ;
Weissbergh, Peter ;
Wood, David ;
Yarnell, John ;
Zamorano, Jose Luis .
EUROPEAN JOURNAL OF CARDIOVASCULAR PREVENTION & REHABILITATION, 2007, 14 :S1-S113
[4]  
Reiner Z, 2011, EUR HEART J, V32, P1769, DOI [10.1016/j.atherosclerosis.2011.06.012, 10.1093/eurheartj/ehr158]