Low-dose, subcutaneous anti-CD20 therapy effectively depletes B-cells and ameliorates CNS autoimmunity

被引:0
|
作者
Huck, C. [1 ]
Wegert, V. [1 ]
Schmid, C. [1 ]
Dunn, B. [2 ]
Smith, P. [1 ]
机构
[1] Novartis Inst BioMed Res, Basel, Switzerland
[2] Novartis Inst Funct Genom Inc, San Diego, CA USA
关键词
D O I
暂无
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
P401
引用
收藏
页码:164 / 164
页数:1
相关论文
共 50 条
  • [1] Low-dose Subcutaneous Anti-CD20 Therapy Effectively Depletes B Cells and Ameliorates Central Nervous System Autoimmunity
    Smith, Paul
    Huck, Catherine
    Wegert, Vanessa
    Schmid, Cindy
    Dunn, Robert
    Leppert, David
    Wallstroem, Erik
    NEUROLOGY, 2017, 88
  • [2] Low-dose Subcutaneous Anti-CD20 Therapy Effectively Depletes B Cells and Ameliorates Central Nervous System Autoimmunity
    Smith, Paul
    Huck, Catherine
    Wegert, Vanessa
    Schmid, Cindy
    Dunn, Robert
    Leppert, David
    Wallstroem, Erik
    NEUROLOGY, 2017, 88
  • [3] Intrathecal anti-CD20 efficiently depletes meningeal B cells in CNS autoimmunity
    Lehmann-Horn, Klaus
    Kinzel, Silke
    Feldmann, Linda
    Radelfahr, Florentine
    Hemmer, Bernhard
    Traffehn, Sarah
    Bernard, Claude C. A.
    Stadelmann, Christine
    Brueck, Wolfgang
    Weber, Martin S.
    ANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGY, 2014, 1 (07): : 490 - 496
  • [4] Low-Dose Subcutaneous Anti-CD20 Treatment Depletes Disease Relevant B Cell Subsets and Attenuates Neuroinflammation
    Huck, Catherine
    Leppert, David
    Wegert, Vanessa
    Schmid, Cindy
    Dunn, Robert
    Weckbecker, Gisbert
    Smith, Paul A.
    JOURNAL OF NEUROIMMUNE PHARMACOLOGY, 2019, 14 (04) : 709 - 719
  • [5] Low-Dose Subcutaneous Anti-CD20 Treatment Depletes Disease Relevant B Cell Subsets and Attenuates Neuroinflammation
    Catherine Huck
    David Leppert
    Vanessa Wegert
    Cindy Schmid
    Robert Dunn
    Gisbert Weckbecker
    Paul A. Smith
    Journal of Neuroimmune Pharmacology, 2019, 14 : 709 - 719
  • [6] BLOCKING B-CELLS (ANTI-CD20/ANTI-CD20)
    Isenberg, David A.
    RHEUMATOLOGY, 2015, 54 : 1 - 1
  • [7] Anti-CD20 treatment depletes B-cells in blood and lymphatic tissue of cynomolgus monkeys
    Schröder, C
    Azimzadeh, AM
    Wu, GS
    Price, JO
    Atkinson, JB
    Pierson, RN
    TRANSPLANT IMMUNOLOGY, 2003, 12 (01) : 19 - 28
  • [8] In-depth B cell immunophenotyping to monitor response to anti-CD20 therapy in CNS autoimmunity
    Su, Elaine
    Wetzel, Nora Sandrine
    Oak, Jean
    Kipp, Lucas
    Han, May H.
    MULTIPLE SCLEROSIS AND RELATED DISORDERS, 2020, 46
  • [9] Anti-CD20 monoclonal antibodies: Beyond B-cells
    Avivi, Irit
    Stroopinsky, Dina
    Katz, Tamar
    BLOOD REVIEWS, 2013, 27 (05) : 217 - 223
  • [10] Subcutaneous Injections of Low-Dose Anti-CD20 Veltuzumab for Treatment of Relapsed Immune Thrombocytopenia (ITP)
    Saleh, Mansoor N.
    Liebman, Howard
    Bernstein, Zalc P.
    Negrea, O. George
    Bussel, James B.
    Onyegbula, Anthony C.
    Farber, Charles M.
    Abassi, Rashid
    Cosgriff, Thomas M.
    Pennington, Kenneth
    Horne, Heather
    Teoh, Nick
    Gomaa, Asraf
    Wegener, William A.
    Goldenberg, David M.
    BLOOD, 2009, 114 (22) : 541 - 541