Adiponectin and leptin increase IL-8 production in human chondrocytes

被引：75

作者：

Gomez, Rodolfo ^{[1
]}

Scotece, Morena ^{[1
]}

Conde, Javier ^{[1
]}

Gomez-Reino, Juan J. ^{[1
]}

Lago, Francisca ^{[2
]}

Gualillo, Oreste ^{[1
]}

机构：

[1] Santiago Univ Clin Hosp, Res Lab 9, NEIRID Lab Neuroendocrine Interact Rheumatol & In, Inst Med Res IDIS,SERGAS, Santiago De Compostela 15706, Spain

[2] Santiago Univ Clin Hosp, Res Lab Mol & Cellular Cardiol 7, Inst Med Res IDIS, SERGAS, Santiago De Compostela 15706, Spain

来源：

ANNALS OF THE RHEUMATIC DISEASES | 2011年 / 70卷 / 11期

关键词：

RHEUMATOID-ARTHRITIS; OSTEOARTHRITIS; INTERLEUKIN-8; PANNUS;

D O I：

10.1136/ard.2010.145672

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：2052 / U207

页数：3

共 11 条

[1] LOCALIZATION OF INTERLEUKIN-8 IN THE SYNOVIAL-MEMBRANE, CARTILAGE-PANNUS JUNCTION AND CHONDROCYTES IN RHEUMATOID-ARTHRITIS [J].

DELEURAN, B ;

LEMCHE, P ;

KRISTENSEN, M ;

CHU, CQ ;

FIELD, M ;

JENSEN, J ;

MATSUSHIMA, K ;

STENGAARDPEDERSEN, K .

SCANDINAVIAN JOURNAL OF RHEUMATOLOGY, 1994, 23 (01) :2-7

[2] Increased serum adiponectin levels in female patients with erosive compared with non-erosive osteoarthritis [J].

Filkova, M. ;

Liskova, M. ;

Hulejova, H. ;

Haluzik, M. ;

Gatterova, J. ;

Pavelkova, A. ;

Pavelka, K. ;

Gay, S. ;

Muller-Ladner, U. ;

Senolt, L. .

ANNALS OF THE RHEUMATIC DISEASES, 2009, 68 (02) :295-296

[3]

Furuzawa-Carballeda J, 2008, CLIN EXP RHEUMATOL, V26, P554

[4] Adipokines in the skeleton: influence on cartilage function and joint degenerative diseases [J].

Gomez, Rodolfo ;

Lago, Francisca ;

Gomez-Reino, Juan ;

Dieguez, Carlos ;

Gualillo, Oreste .

JOURNAL OF MOLECULAR ENDOCRINOLOGY, 2009, 43 (1-2) :11-18

[5] Adiponectin stimulates IL-8 production by rheumatoid synovial fibroblasts [J].

Kitahara, Kanako ;

Kusunoki, Natsuko ;

Kakiuchi, Terutaka ;

Suguro, Toru ;

Kawai, Shinichi .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2009, 378 (02) :218-223

[6] The infrapatellar fat pad of patients with osteoarthritis has an inflammatory phenotype [J].

Klein-Wieringa, I. R. ;

Kloppenburg, M. ;

Bastiaansen-Jenniskens, Y. M. ;

Yusuf, E. ;

Kwekkeboom, J. C. ;

El-Bannoudi, H. ;

Nelissen, R. G. H. H. ;

Zuurmond, A. ;

Stojanovic-Susulic, V. ;

Van Osch, G. J. V. M. ;

Toes, R. E. M. ;

Ioan-Facsinay, A. .

ANNALS OF THE RHEUMATIC DISEASES, 2011, 70 (05) :851-857

[7] Inflammatory infiltrate and interleukin-8 expression in the synovium of psoriatic arthritis - an immunohistochemical and mRNA analysis [J].

Konig, A ;

Krenn, V ;

Gillitzer, R ;

Glockner, J ;

Janssen, E ;

Gohlke, F ;

Eulert, J ;

Muller-Hermelink, HK .

RHEUMATOLOGY INTERNATIONAL, 1997, 17 (04) :159-168

[8] A new player in cartilage homeostasis: adiponectin induces nitric oxide synthase type II and pro-inflammatory cytokines in chondrocytes [J].

Lago, R. ;

Gomez, R. ;

Otero, M. ;

Lago, F. ;

Gallego, R. ;

Dieguez, C. ;

Gomez-Reino, J. J. ;

Gualillo, O. .

OSTEOARTHRITIS AND CARTILAGE, 2008, 16 (09) :1101-1109

[9] IL-8/CXCL8 and growth-related oncogene α/CXCL1 induce chondrocyte hypertrophic differentiation [J].

Merz, D ;

Liu, R ;

Johnson, K ;

Terkeltaub, R .

JOURNAL OF IMMUNOLOGY, 2003, 171 (08) :4406-4415

[10] Changes in plasma levels of fat-derived hormones adiponectin, leptin, resistin and visfatin in patients with rheumatoid arthritis [J].