High prevalence of viral genomes and inflammation in peripartum cardiomyopathy

被引:129
作者
Bültmann, BD
Klingel, K
Näbauer, M
Wallwiener, D
Kandolf, R
机构
[1] Univ Tubingen Hosp, Inst Pathol, D-72076 Tubingen, Germany
[2] Univ Tubingen Hosp, Dept Gynecol & Obstet, D-72076 Tubingen, Germany
[3] Univ Munich, Dept Med 1, Munich, Germany
关键词
peripartum cardiomyopathy; virus; molecular pathologic data; infiammatory cardiomyopathy;
D O I
10.1016/j.ajog.2005.01.022
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Molecular pathologic investigation of endomyocardial biopsy specimens from 26 patients with peripartum cardiomyopathy revealed viral genomes (parvovirus B19, human herpes virus 6, Epstein-Barr virus, and human cytomegalovirus) in 8 patients (30.7%) that were associated immunohistologically with interstitial inflammation. These findings indicate a high prevalence of virus-associated inflammatory changes in peripartum cardiomyopathy. (c) 2005 Elsevier Inc. All rights reserved.
引用
收藏
页码:363 / 365
页数:3
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