Molecular pathologic investigation of endomyocardial biopsy specimens from 26 patients with peripartum cardiomyopathy revealed viral genomes (parvovirus B19, human herpes virus 6, Epstein-Barr virus, and human cytomegalovirus) in 8 patients (30.7%) that were associated immunohistologically with interstitial inflammation. These findings indicate a high prevalence of virus-associated inflammatory changes in peripartum cardiomyopathy. (c) 2005 Elsevier Inc. All rights reserved.
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Bültmann BD, 2004, NEW ENGL J MED, V350, P2006
机构:
Virginia Commonwealth Univ, Dept Med, Dept Pediat, Div Infect Dis, Richmond, VA 23298 USAVirginia Commonwealth Univ, Dept Med, Dept Pediat, Div Infect Dis, Richmond, VA 23298 USA
机构:
Virginia Commonwealth Univ, Dept Med, Dept Pediat, Div Infect Dis, Richmond, VA 23298 USAVirginia Commonwealth Univ, Dept Med, Dept Pediat, Div Infect Dis, Richmond, VA 23298 USA