Electrochemical synthesis of spiroisoxazole derivatives and its application to natural products

被引：0

作者：

Ogamino, T ^{[1
]}

Ishikawa, Y ^{[1
]}

Nishiyama, S ^{[1
]}

机构：

[1] Keio Univ, Fac Sci & Technol, Dept Chem, Kohoku Ku, Yokohama, Kanagawa 2238522, Japan

来源：

HETEROCYCLES | 2003年 / 61卷

关键词：

spiroisoxazole; anodic oxidation; zamamistatin; dibromophenylpyruvic acid oxime; phenolic oxidation;

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Efficient synthesis of the trans-spiroisoxazole (1) and its unnatural cis-isomer (2) was accomplished by employing anodic oxidation of 4, followed by Zn(BH4)(2) reduction. This method was applied to an assembly of the carbon framework of zamamistatin (12).

引用

页码：73 / +

页数：7