Antibacterial and antiviral metabolites from cyanobacteria: Their application and their impact on human health

被引：37

作者：

Carpine, Roberta ^{[1
]}

Sieber, Simon ^{[1
]}

机构：

[1] Univ Zurich, Dept Chem, Winterthurerstr 190, CH-8057 Zurich, Switzerland

来源：

CURRENT RESEARCH IN BIOTECHNOLOGY | 2021年 / 3卷

关键词：

Cyanobacteria; Natural products; Antibacterial; Antiviral; Biotechnological application; Human health; FRESH-WATER CYANOBACTERIUM; MANNAN-BINDING LECTIN; HERPES SIMPLEX VIRUS; HEPATITIS-C VIRUS; ANTI-HIV ACTIVITY; CYANOVIRIN-N; MICROCYSTIS-AERUGINOSA; NATURAL-PRODUCTS; CALCIUM SPIRULAN; LYNGBYA-MAJUSCULA;

D O I：

10.1016/j.crbiot.2021.03.001

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Bacterial and viral infections pose a direct threat to human health due to the increase of drug-resistant and novel pathogenic strains. Natural products represent a prolific source of bioactive metabolites, which have been exploited for their therapeutic effects. In particular, cyanobacteria were identified as important producers of secondary metabolites possessing antibacterial and antiviral activities, among others. A meta-analysis indi-cated that some natural product classes target bacteria or viruses exclusively. This result also applied for some cyanobacterial species that were identified to produce only antibacterial or antiviral compounds. Furthermore, cyanobacteria represent a promising host for bio-production due to their ability to perform photosynthesis and their low-cost production requirements. This review highlights antibacterial and antiviral compounds isol iso-lated from cyanobacteria and the biotechnological application of these organisms .

引用

页码：65 / 81

页数：17

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