[1] Univ Sheffield, Dept Paediat, Sheffield, S Yorkshire, England
[2] Univ Sheffield, Sch Med, Dept Human Metab & Clin Biochem, Sheffield S10 2RX, S Yorkshire, England
[3] Univ Sheffield, Dept Gastroenterol, Sheffield, S Yorkshire, England
[4] Univ Sheffield, Liver Unit, Sheffield, S Yorkshire, England