A selective, cell-permeable fluorescent probe for Al3+ in living cells

被引：154

作者：

Wang, Lina ^{[1
,2
]}

Qin, Wenwu ^{[1
,2
]}

Tang, Xiaoliang ^{[1
,2
]}

Dou, Wei ^{[1
,2
]}

Liu, Weisheng ^{[1
,2
]}

Teng, Qingfeng ^{[1
,2
]}

Yao, Xiaojun ^{[1
,2
]}

机构：

[1] Lanzhou Univ, Key Lab Nonferrous Met Chem & Resources Utilizat, Coll Chem & Chem Engn, Lanzhou 730000, Peoples R China

[2] Lanzhou Univ, State Key Lab Appl Organ Chem, Coll Chem & Chem Engn, Lanzhou 730000, Peoples R China

来源：

ORGANIC & BIOMOLECULAR CHEMISTRY | 2010年 / 8卷 / 16期

关键词：

METAL-COMPLEXES; ALUMINUM; TOXICITY; ACID; RECOGNITION; CHEMOSENSOR; SWITCHES; SENSORS; WATER; IONS;

D O I：

10.1039/c0ob00123f

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis and evaluation of a novel Schiff-base fluorescent probe L for detection of Al3+ are described. The structure of L was determined by X-ray and other spectroscopic data. The fluorescent spectra changes and microscopy images show that indicator L is highly selective for Al3+ not only in abiotic systems but also in living cells. Other metal ions failed to respond. The new probe could be used as an efficient tool for Al3+ monitoring in the environment and biological systems.

引用

页码：3751 / 3757

页数：7

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