Addition of organocopper reagents to N-alkylpyridinium salts.: A flexible access to polysubstituted dihydropyridines

被引:25
作者
Bennasar, ML [1 ]
Juan, C [1 ]
Bosch, J [1 ]
机构
[1] Univ Barcelona, Fac Pharm, Organ Chem Lab, E-08028 Barcelona, Spain
关键词
acylation; copper and compounds; pyridines; pyridinium salts;
D O I
10.1016/S0040-4039(00)02006-2
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
The addition of a series of organocopper (alkyl, vinyl, allyl, and ethynyl) reagents to 3-acyl-N-alkylpyridinium salts, followed by acylation of the intermediate 1,4- or 1,2-dihydropyridines with trichloroacetic anhydride has been studied. (C) 2001 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:585 / 588
页数:4
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