Highly Porous Composite Hydrogel Materials Based on β-Ca3(PO4)2/Polyethylene Glycol Diacrylate

被引：0
|
作者：
Evdokimov, P. V. [1 ,2 ]
Kiseleva, A. K. [2 ]
Shibaev, A. V. [2 ]
Filippova, O. E. [2 ]
Novoseletskaya, E. S. [2 ]
Efimenko, A. Yu. [2 ]
Scherbakov, I. M. [2 ]
Shipunov, G. A. [2 ]
Dubrov, V. E. [2 ]
Putlayev, V. I. [2 ]
机构：
[1] Kurnakov Inst Gen & Inorgan Chem, Moscow 119991, Russia
[2] Moscow MV Lomonosov State Univ, Moscow 119991, Russia
来源：
INORGANIC MATERIALS-APPLIED RESEARCH | 2022年 / 13卷 / 05期
基金：
俄罗斯科学基金会;
关键词：
biomaterials; bone tissue regeneration; calcium phosphate; hydrogel; composite; macroporosity; TISSUE; BIOMATERIALS; SCAFFOLD;
D O I：
10.1134/S2075113322050094
中图分类号：
T [工业技术];
学科分类号：
08 ;
摘要：
The possibility of obtaining highly porous hydrogel composite materials for biomedical applications based on tricalcium phosphate in a polyethylene glycol diacrylate matrix, aimed at repairing bone defects, has been studied. The effect of different content of inorganic filler particles exerted on the mechanical characteristics of highly porous hydrogel composites beta-Ca-3(PO4)(2)/polyethylene glycol diacrylate has been studied. It is demonstrated that the preparation of highly porous composite materials with specified elastic properties is quite possible. The viscoelastic properties of the obtained materials are shown to depend on the preset pore size. Varying the tricalcium phosphate fraction in the highly porous hydrogel material makes it possible to control the relative stiffness of the composite.
引用
收藏
页码：1290 / 1295
页数：6
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